Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 7/20 | 0.53 |
| ▸ | LPAR1 | Q92633 | 5/20 | 0.53 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.53 |
| ▸ | PRKD3 | O94806 | 3/20 | 0.47 |
| ▸ | PRKCG | P05129 | 3/20 | 0.47 |
| ▸ | PRKCB | P05771 | 3/20 | 0.47 |
| ▸ | PRKCA | P17252 | 3/20 | 0.47 |
| ▸ | PRKCH | P24723 | 3/20 | 0.47 |
| ▸ | PRKCI | P41743 | 3/20 | 0.47 |
| ▸ | PRKCE | Q02156 | 3/20 | 0.47 |
| ▸ | PRKCQ | Q04759 | 3/20 | 0.47 |
| ▸ | PRKCZ | Q05513 | 3/20 | 0.47 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.47 |
| ▸ | PRKD1 | Q15139 | 3/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.45 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.42 |
| ▸ | FDPS | P14324 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11125417 | 0.84 | PRKD3 (0.52) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL11089217 | 0.83 | ENPP2 (0.57) | LPAR3LPAR1LPAR2ENPP2SMPD1 | |
| Phosphoric Acid SCHEMBL11087300 | 0.83 | PRKD3 (0.53) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL11087950 | 0.82 | ENPP2 (0.58) | LPAR3LPAR1LPAR2PRKD3PRKCG | |
| SCHEMBL8677600 | 0.82 | ENPP2 (0.58) | LPAR3LPAR1LPAR2PRKD3PRKCG | |
| SCHEMBL11078070 | 0.82 | ENPP2 (0.58) | LPAR3LPAR1LPAR2PRKD3PRKCG | |
| SCHEMBL11081529 | 0.82 | LPAR3 (0.59) | LPAR3LPAR1LPAR2PRKD3PRKCG | |
| SCHEMBL11090082 | 0.80 | ENPP2 (0.50) | LPAR3LPAR1LPAR2PRKD3PRKCG | |
| SCHEMBL11087655 | 0.79 | LPAR3 (0.71) | LPAR3LPAR1LPAR2 | |
| SCHEMBL11081212 | 0.79 | LPAR3 (0.71) | LPAR3LPAR1LPAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4444766-A | ANTITUMOR | BOEHRINGER MANNHEIM GMBH (DE) | 1984-04-24 | — | — | US | disclosed |