Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 6/20 | 0.57 |
| ▸ | LPAR3 | Q9UBY5 | 8/20 | 0.50 |
| ▸ | LPAR1 | Q92633 | 7/20 | 0.50 |
| ▸ | SGPL1 | O95470 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | LPAR5 | Q9H1C0 | 4/20 | 0.44 |
| ▸ | LPAR6 | P43657 | 3/20 | 0.44 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.44 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.44 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11083114 | 0.91 | LPAR3 (0.61) | ENPP2LPAR3LPAR1LPAR5LPAR6 | |
| SCHEMBL9797511 | 0.88 | ENPP2 (0.66) | ENPP2LPAR3LPAR1SGPL1SMN1; SMN2 | |
| SCHEMBL11087950 | 0.87 | ENPP2 (0.58) | ENPP2LPAR3LPAR1SMN1; SMN2LPAR5 | |
| SCHEMBL8677600 | 0.87 | ENPP2 (0.58) | ENPP2LPAR3LPAR1SMN1; SMN2LPAR5 | |
| SCHEMBL11078070 | 0.87 | ENPP2 (0.58) | ENPP2LPAR3LPAR1SMN1; SMN2LPAR5 | |
| SCHEMBL11082144 | 0.87 | ENPP2 (0.52) | ENPP2LPAR3LPAR1SGPL1SMN1; SMN2 | |
| SCHEMBL11090082 | 0.84 | ENPP2 (0.50) | ENPP2LPAR3LPAR1SGPL1SMN1; SMN2 | |
| SCHEMBL11087305 | 0.83 | LPAR3 (0.53) | ENPP2LPAR3LPAR1LPAR2SMPD1 | |
| SCHEMBL11089856 | 0.83 | ENPP2 (0.54) | ENPP2LPAR3LPAR1SGPL1SMN1; SMN2 | |
| Phosphoric Acid SCHEMBL11089195 | 0.82 | SMPD1 (0.42) | ENPP2SMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4444766-A | ANTITUMOR | BOEHRINGER MANNHEIM GMBH (DE) | 1984-04-24 | — | — | US | disclosed |