Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.45 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2783065 | 0.71 | ALDH1A1 (0.59) | HDAC6ALDH1A1KDM4EHPGDGAA | |
| SCHEMBL29724622 | 0.71 | ALDH1A1 (0.59) | HDAC6ALDH1A1KDM4EHPGDGAA | |
| SCHEMBL11083836 | 0.71 | PLK1 (0.40) | ADORA3ADORA2BALDH1A1KDM4EHPGD | |
| SCHEMBL4201351 | 0.69 | TP53 (0.42) | ADORA3ALDH1A1KDM4EHPGDGAA | |
| SCHEMBL11090049 | 0.68 | GABRA5 (0.49) | ADORA3DAOADORA1ADORA2BALDH1A1 | |
| SCHEMBL11084726 | 0.68 | ADORA3 (0.52) | ADORA3ALDH1A1KDM4EHPGDGAA | |
| SCHEMBL18691788 | 0.68 | KMT2A (0.44) | ADORA3HDAC6ALDH1A1KDM4EHPGD | |
| SCHEMBL11403965 | 0.67 | ADORA3 (0.46) | ADORA3DAOHDAC6ALDH1A1KDM4E | |
| SCHEMBL31093975 | 0.66 | GABRA5 (0.55) | ADORA3DAOADORA1ALDH1A1KDM4E | |
| SCHEMBL1278798 | 0.66 | GABRA5 (0.55) | ADORA3DAOADORA1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4440929-A | Imidazoquinoxaline compounds | USV PHARMACEUTICAL CORPORATION (US) | 1984-04-03 | — | — | US | disclosed |