Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | RBP4 | P02753 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | AR | P10275 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1491206 | 0.81 | KMT2A (0.64) | ALOX15SMN1; SMN2GAAKMT2AMEN1 | |
| SCHEMBL2857040 | 0.81 | AKR1C3 (0.64) | KDM4ERBP4SMN1; SMN2GAAKMT2A | |
| SCHEMBL29664576 | 0.80 | ADRA2C (0.58) | KDM4EALOX15RBP4TSHRSMN1; SMN2 | |
| SCHEMBL3958403 | 0.80 | ADRA2C (0.58) | KDM4EALOX15RBP4TSHRSMN1; SMN2 | |
| SCHEMBL5234913 | 0.80 | KDM4E (0.73) | KDM4EALOX15TSHRSMN1; SMN2GAA | |
| SCHEMBL113679 | 0.80 | ALDH1A1 (0.55) | KDM4EALOX15RBP4TSHRSMN1; SMN2 | |
| SCHEMBL631024 | 0.80 | AKR1C3 (0.65) | TSHRKMT2AAKR1C3LMNAALDH1A1 | |
| SCHEMBL11093641 | 0.79 | GAA (0.72) | KDM4EALOX15TSHRSMN1; SMN2GAA | |
| SCHEMBL5238054 | 0.79 | HTR1A (0.57) | KDM4EALOX15RBP4TSHRKMT2A | |
| SCHEMBL11091267 | 0.79 | SMN1; SMN2 (0.50) | TSHRSMN1; SMN2KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4469694-A | 2-(1-Piperazinyl)-2,4,6-cycloheptatrien-1-one derivatives | AYERST, MCKENNA & HARRISON INC. (CA) | 1984-09-04 | — | — | US | disclosed |