SCHEMBL11087764

SCHEMBL11087764

COc1ccc2[nH]c(C)c(CC(=O)Oc3ccc(C(=O)OCCN4CCN(CCN5CCOCC5)CC4)cc3)c2c1

nearest known ligand 0.58

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 1/20 0.54
ALDH1A1 P00352 7/20 0.52
AKR1C2 P52895 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
CYP1A2 P05177 1/20 0.47
KDM4E B2RXH2 6/20 0.47
HPGD P15428 2/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
ATM Q13315 1/20 0.47
HSD17B10 Q99714 3/20 0.45
ALOX15 P16050 1/20 0.45
MAPT P10636 1/20 0.44
KDR P35968 1/20 0.44
GAA P10253 1/20 0.44
MTNR1A P48039 1/20 0.43
MTNR1B P49286 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11093044 0.99 PTGS2 (0.53) PTGS2ALDH1A1AKR1C2SMN1; SMN2CYP1A2
SCHEMBL11192813 0.99 PTGS2 (0.55) PTGS2ALDH1A1AKR1C2SMN1; SMN2CYP1A2
Hydrochloric Acid SCHEMBL11223300 0.98 PTGS2 (0.54) PTGS2ALDH1A1AKR1C2SMN1; SMN2CYP1A2
SCHEMBL11089661 0.93 ALDH1A1 (0.49) PTGS2ALDH1A1AKR1C2SMN1; SMN2CYP1A2
SCHEMBL11093024 0.93 PTGS2 (0.48) PTGS2ALDH1A1AKR1C2SMN1; SMN2CYP1A2
Hydrochloric Acid SCHEMBL11081771 0.92 ALDH1A1 (0.49) PTGS2ALDH1A1AKR1C2SMN1; SMN2CYP1A2
SCHEMBL11093304 0.92 AKR1C2 (0.51) PTGS2ALDH1A1AKR1C2SMN1; SMN2KDM4E
Hydrochloric Acid SCHEMBL11089910 0.92 AKR1C2 (0.50) PTGS2ALDH1A1AKR1C2SMN1; SMN2KDM4E
SCHEMBL11197586 0.91 HSD17B10 (0.55) PTGS2ALDH1A1AKR1C2KDM4EHPGD
SCHEMBL11087847 0.88 AKR1C2 (0.46) PTGS2ALDH1A1AKR1C2SMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-219810472-U Mounting device for FK401 input star wheel sensor of smoke machine equipment 红塔烟草(集团)有限责任公司 2023-10-10 CN claimed
JP-58092659-A None JP disclosed
US-20250378924-A1 INTEGRATED PHENOTYPE ENGINE FOR DATA PROCESSING, MODELING, AND INTEROPERABILITY The Government of the United States of America, as represented by the Secretary of Homeland Security (US) 2025-12-11 US disclosed
US-12394506-B2 Platform for collaborative analysis of electronic records The Government of the United States of America, represented by the Secretary of Homeland Security (US) 2025-08-19 US disclosed
US-12237058-B2 AI-enhanced, user programmable, socially networked system The Government of the United States of America, represented by the Secretary of Homeland Security (US) 2025-02-25 US disclosed
US-20240185971-A1 AI-ENHANCED, USER PROGRAMMABLE, SOCIALLY NETWORKED SYSTEM The Government of the United States of America, as represented by the Secretary of Homeland Security (US) 2024-06-06 US disclosed
US-11908555-B2 AI-enhanced, user programmable, socially networked system The Government of the United States of America, as represented by the Secretary of Homeland Security (US) 2024-02-20 US disclosed
CN-219810472-U Mounting device for FK401 input star wheel sensor of smoke machine equipment 红塔烟草(集团)有限责任公司 2023-10-10 CN disclosed
CN-219810472-U Mounting device for FK401 input star wheel sensor of smoke machine equipment 红塔烟草(集团)有限责任公司 2023-10-10 CN disclosed
CN-219810472-U Mounting device for FK401 input star wheel sensor of smoke machine equipment 红塔烟草(集团)有限责任公司 2023-10-10 CN disclosed
US-20220310276-A1 PLATFORM FOR COLLOBARATIVE ANALYSIS OF ELECTRONIC RECORDS The Government of the United States of America, as represented by the Secretary of Homeland Security (US) 2022-09-29 US disclosed
US-20220310218-A1 AI-ENHANCED, USER PROGRAMMABLE, SOCIALLY NETWORKED SYSTEM The Government of the United States of America, as represented by the Secretary of Homeland Security (US) 2022-09-29 US disclosed
CN-114767646-A Effects of gastric retentive bile acid sequestrant formulation 铁木医药有限公司 2022-07-22 CN disclosed
EP-3991719-A1 GASTRO-RETENTIVE SUSTAINED-RELEASE ORAL DOSAGE FORM OF A BILE ACID SEQUESTRANT Ironwood Pharmaceuticals, Inc. (US) 2022-05-04 EP disclosed
US-20220110876-A1 Gastro-Retentive Sustained-Release Oral Dosage Form of a Bile Acid Sequestrant IRONWOOD PHARMACEUTICALS INC (US) 2022-04-14 US disclosed
CN-108057028-A The Entogastric lingering peroral dosage form of the enteric coating of tablet form and its application and pharmaceutical composition 铁木医药有限公司 2018-05-22 CN disclosed
US-4443603-A PROTEOLYTIC ENZYME INHIBITORS KOWA COMPANY LIMITED (JP) 1984-04-17 US disclosed
JP-S5892659-A ANTIULCER KOWA CO 1983-06-02 JP disclosed
EP-0071433-A1 Medicine for the treatment of diabetes KOWA COMPANY, LTD. (JP) 1983-02-09 EP disclosed
EP-0067561-A2 Piperazine derivatives and processes for producing them KOWA COMPANY, LTD. (JP) 1982-12-22 EP disclosed