Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11087764 | 0.93 | PTGS2 (0.54) | PTGS2ALDH1A1KDM4EHPGDAKR1C2 | |
| Hydrochloric Acid SCHEMBL11093044 | 0.92 | PTGS2 (0.53) | PTGS2ALDH1A1KDM4EHPGDAKR1C2 | |
| SCHEMBL11192813 | 0.92 | PTGS2 (0.55) | PTGS2ALDH1A1KDM4EHPGDAKR1C2 | |
| Hydrochloric Acid SCHEMBL11223300 | 0.92 | PTGS2 (0.54) | PTGS2ALDH1A1KDM4EHPGDAKR1C2 | |
| SCHEMBL11089661 | 0.88 | ALDH1A1 (0.49) | PTGS2ALDH1A1KDM4EHPGDAKR1C2 | |
| Hydrochloric Acid SCHEMBL11081771 | 0.87 | ALDH1A1 (0.49) | PTGS2ALDH1A1KDM4EHPGDAKR1C2 | |
| SCHEMBL11093304 | 0.87 | AKR1C2 (0.51) | PTGS2ALDH1A1KDM4EHPGDAKR1C2 | |
| Hydrochloric Acid SCHEMBL11089910 | 0.87 | AKR1C2 (0.50) | PTGS2ALDH1A1KDM4EHPGDAKR1C2 | |
| SCHEMBL11197586 | 0.86 | HSD17B10 (0.55) | PTGS2ALDH1A1KDM4EHPGDAKR1C2 | |
| SCHEMBL11087847 | 0.83 | AKR1C2 (0.46) | PTGS2ALDH1A1KDM4EHPGDAKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4443603-A | PROTEOLYTIC ENZYME INHIBITORS | KOWA COMPANY LIMITED (JP) | 1984-04-17 | — | — | US | disclosed |