Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | NPC1 | O15118 | 5/20 | 0.56 |
| ▸ | RAB9A | P51151 | 5/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | ABL1 | P00519 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 7/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3603750 | 0.88 | MAPT (0.55) | ALDH1A1NPC1RAB9AHSD17B10SMN1; SMN2 | |
| SCHEMBL3606683 | 0.86 | CSNK2A1 (0.58) | NPC1RAB9ASMN1; SMN2ABL1MEN1 | |
| SCHEMBL3615150 | 0.86 | MEN1 (0.55) | ALDH1A1NPC1RAB9AHSD17B10SMN1; SMN2 | |
| SCHEMBL3609767 | 0.86 | PHGDH (0.55) | ALDH1A1NPC1RAB9AHSD17B10SMN1; SMN2 | |
| Bromide SCHEMBL7142457 | 0.85 | CSNK2A1 (0.57) | ALDH1A1NPC1RAB9ASMN1; SMN2ABL1 | |
| Hydrochloric Acid SCHEMBL10748142 | 0.85 | ALDH1A1 (0.53) | ALDH1A1NPC1RAB9AHSD17B10SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL10748139 | 0.85 | ALDH1A1 (0.53) | ALDH1A1NPC1RAB9AHSD17B10SMN1; SMN2 | |
| SCHEMBL11090239 | 0.85 | MAPT (0.51) | ALDH1A1NPC1RAB9AHSD17B10SMN1; SMN2 | |
| SCHEMBL23705337 | 0.85 | NPC1 (0.55) | ALDH1A1NPC1RAB9AHSD17B10SMN1; SMN2 | |
| SCHEMBL11090908 | 0.85 | MAPT (0.50) | ALDH1A1NPC1RAB9AHSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4452985-A | 2-Guanyl-4-(substituted phenyl) thiazole derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1984-06-05 | — | — | US | disclosed |