Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CDK1 | P06493 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11082739 | 0.94 | GAA (0.55) | TSHRGAACDK1KDM4ENPC1 | |
| SCHEMBL11089942 | 0.91 | SMN1; SMN2 (0.48) | SMN1; SMN2TSHRGAACDK1KDM4E | |
| SCHEMBL11089977 | 0.91 | LMNA (0.46) | SMN1; SMN2TSHRGAAKDM4ENPC1 | |
| SCHEMBL11086619 | 0.89 | GAA (0.51) | SMN1; SMN2TSHRGAACDK1KDM4E | |
| SCHEMBL11088741 | 0.87 | GAA (0.49) | SMN1; SMN2TSHRGAACDK1MAPT | |
| SCHEMBL10566570 | 0.85 | TSHR (0.50) | SMN1; SMN2TSHRGAACDK1KDM4E | |
| SCHEMBL10389125 | 0.85 | TSHR (0.50) | SMN1; SMN2TSHRGAACDK1KDM4E | |
| SCHEMBL11092594 | 0.85 | GAA (0.54) | SMN1; SMN2TSHRGAACDK1KDM4E | |
| SCHEMBL10672734 | 0.84 | GAA (0.53) | SMN1; SMN2TSHRGAACDK1MAPT | |
| SCHEMBL11088631 | 0.84 | ALDH1A1 (0.50) | SMN1; SMN2TSHRGAACDK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0023141-B1 | HERBICIDAL SULFONAMIDES, PREPARATION AND USE THEREOF, COMPOSITIONS CONTAINING THEM, INTERMEDIATES THEREFOR AND PREPARATION OF SUCH INTERMEDIATES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-04-11 | — | — | EP | claimed |
| US-4310346-A | HERBICIDES AND PLANT GROWTH REGULATORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-01-12 | — | — | US | claimed |
| EP-0023141-A2 | Herbicidal sulfonamides, preparation and use thereof, compositions containing them, intermediates therefor and preparation of such intermediates | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-01-28 | — | — | EP | claimed |
| EP-0023141-B1 | HERBICIDAL SULFONAMIDES, PREPARATION AND USE THEREOF, COMPOSITIONS CONTAINING THEM, INTERMEDIATES THEREFOR AND PREPARATION OF SUCH INTERMEDIATES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-04-11 | — | — | EP | disclosed |
| US-4417917-A | BENZENE DISULFONIC ACID DERIVATIVES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-11-29 | — | — | US | disclosed |
| US-4310346-A | HERBICIDES AND PLANT GROWTH REGULATORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-01-12 | — | — | US | disclosed |
| EP-0023141-A2 | Herbicidal sulfonamides, preparation and use thereof, compositions containing them, intermediates therefor and preparation of such intermediates | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-01-28 | — | — | EP | disclosed |