Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11087777 | 0.91 | SMN1; SMN2 (0.49) | ALDH1A1NPC1KDM4EGAAMAPT | |
| SCHEMBL11092529 | 0.90 | LMNA (0.45) | LMNAALDH1A1NPC1KDM4EGAA | |
| SCHEMBL11092110 | 0.89 | NPC1 (0.45) | ALDH1A1NPC1KDM4EMAPTTSHR | |
| SCHEMBL11055373 | 0.88 | NPC1 (0.44) | ALDH1A1NPC1KDM4EMAPTTSHR | |
| SCHEMBL10838060 | 0.87 | GAA (0.46) | LMNAALDH1A1NPC1KDM4EGAA | |
| SCHEMBL11082739 | 0.85 | GAA (0.55) | ALDH1A1NPC1KDM4EGAAMAPT | |
| SCHEMBL9833936 | 0.85 | ALDH1A1 (0.43) | LMNAALDH1A1NPC1GAATSHR | |
| SCHEMBL9833941 | 0.85 | ALDH1A1 (0.43) | LMNAALDH1A1NPC1GAATSHR | |
| SCHEMBL11088631 | 0.84 | ALDH1A1 (0.50) | ALDH1A1NPC1KDM4EGAAMAPT | |
| SCHEMBL11086570 | 0.83 | ALDH1A1 (0.47) | ALDH1A1NPC1KDM4EGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0023141-B1 | HERBICIDAL SULFONAMIDES, PREPARATION AND USE THEREOF, COMPOSITIONS CONTAINING THEM, INTERMEDIATES THEREFOR AND PREPARATION OF SUCH INTERMEDIATES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-04-11 | — | — | EP | claimed |
| US-4310346-A | HERBICIDES AND PLANT GROWTH REGULATORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-01-12 | — | — | US | claimed |
| EP-0023141-A2 | Herbicidal sulfonamides, preparation and use thereof, compositions containing them, intermediates therefor and preparation of such intermediates | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-01-28 | — | — | EP | claimed |
| EP-0023141-B1 | HERBICIDAL SULFONAMIDES, PREPARATION AND USE THEREOF, COMPOSITIONS CONTAINING THEM, INTERMEDIATES THEREFOR AND PREPARATION OF SUCH INTERMEDIATES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-04-11 | — | — | EP | disclosed |
| US-4417917-A | BENZENE DISULFONIC ACID DERIVATIVES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-11-29 | — | — | US | disclosed |
| EP-0023141-A2 | Herbicidal sulfonamides, preparation and use thereof, compositions containing them, intermediates therefor and preparation of such intermediates | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-01-28 | — | — | EP | disclosed |