Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GSK3B | P49841 | 3/20 | 0.37 |
| ▸ | NFATC1 | O95644 | 2/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10809160 | 0.99 | GAA (0.39) | GAANPSR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10807449 | 0.90 | DYRK1A (0.46) | GAANPSR1NPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL10999820 | 0.89 | GSK3B (0.39) | GSK3BNFATC1DYRK1AALDH1A1HTR6 | |
| SCHEMBL10806776 | 0.88 | ALDH1A1 (0.42) | GAANPSR1GSK3BDYRK1AMEN1 | |
| Hydrochloric Acid SCHEMBL10999689 | 0.86 | ALDH1A1 (0.41) | GAANPSR1GSK3BDYRK1AMEN1 | |
| SCHEMBL18293342 | 0.84 | MEN1 (0.46) | GAANPSR1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL10809122 | 0.84 | GSK3B (0.41) | GSK3BNFATC1DYRK1AMAPTALDH1A1 | |
| SCHEMBL7308514 | 0.84 | GAA (0.51) | GAANPSR1NPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL10808602 | 0.83 | GSK3B (0.40) | GSK3BNFATC1DYRK1AMAPTALDH1A1 | |
| SCHEMBL1467146 | 0.82 | LMNA (0.43) | GAANPSR1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4479955-A | ANTICONVULSANTS, ANTIDEPRESSANTS, ANTIEPILEPTIC AGENTS | CIBA-GEIGY CORPORATION (US) | 1984-10-30 | — | — | US | claimed |