Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.47 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HRH2 | P25021 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.47 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11179694 | 0.95 | ADRA2A (0.47) | LMNAADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL11080580 | 0.91 | KMT2A (0.48) | LMNAADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL10972914 | 0.91 | ADRA2A (0.52) | LMNAADRA2AADRA2BADRA2CADRA1D | |
| Hydrochloric Acid SCHEMBL10975432 | 0.90 | ADRA2A (0.54) | LMNAADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL10975965 | 0.87 | ADRA2A (0.51) | LMNAADRA2AADRA2BADRA2CADRA1D | |
| Hydrochloric Acid SCHEMBL11183992 | 0.86 | KMT2A (0.46) | LMNAADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL11085492 | 0.86 | ADRA1D (0.45) | LMNAADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL10972755 | 0.85 | CFB (0.49) | LMNAADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL10975728 | 0.85 | LMNA (0.47) | LMNAADRA2AADRA2BADRA2CADRA1D | |
| Hydrochloric Acid SCHEMBL10976009 | 0.85 | ADRA2A (0.51) | LMNAADRA2AADRA2BADRA2CADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4466966-A | N-aryl-N'-(1,4,5,6-tetrahydropyrimidin-2-yl)ureas for intestinal disorders | MCNEILAB, INC. (US) | 1984-08-21 | — | — | US | disclosed |
| US-4285948-A | ADMINISTERING CARDIOTONIC AGENTS | MCNEILAB, INC. (US) | 1981-08-25 | — | — | US | disclosed |