Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | SLC9A1 | P19634 | 5/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14299004 | 0.89 | TSHR (0.46) | TSHRNPSR1RXFP1SLC9A1HDAC3 | |
| SCHEMBL8804149 | 0.82 | TSHR (0.50) | TSHRNPSR1RXFP1SLC9A1HDAC3 | |
| SCHEMBL76069 | 0.82 | SMN1; SMN2 (0.49) | TSHRSMN1; SMN2KMT2ANPC1RAB9A | |
| SCHEMBL29394827 | 0.82 | SMN1; SMN2 (0.49) | TSHRSMN1; SMN2KMT2ANPC1RAB9A | |
| SCHEMBL14244153 | 0.80 | TSHR (0.48) | TSHRNPSR1RXFP1SLC9A1HDAC3 | |
| SCHEMBL8804817 | 0.80 | TSHR (0.50) | TSHRNPSR1RXFP1SLC9A1HDAC3 | |
| SCHEMBL8806232 | 0.79 | TSHR (0.48) | TSHRNPSR1RXFP1SLC9A1HDAC3 | |
| SCHEMBL1186715 | 0.79 | FAAH (0.44) | TSHRSMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL8889223 | 0.78 | TSHR (0.45) | TSHRNPSR1RXFP1SLC9A1HDAC3 | |
| SCHEMBL11088928 | 0.76 | TSHR (0.50) | TSHRNPSR1RXFP1SLC9A1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 248 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1556039-A2 | PROCESS FOR THE PREPARATION OF TRI-NITROGEN CONTAINING HETEROARYL-DIAMINE DERIVATIVES USEFUL AS PHARMACEUTICAL AGENTS AND METHODS OF PRODUCING PHARMACEUTICAL AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-07-27 | — | — | EP | claimed |
| US-20040077878-A1 | Process for the preparation of tri-nitrogen containing heteroaryl-diamine derivatives useful as pharmaceutical agents and methods of producing pharmaceutical agents | LIU CHUNJIAN (US) | 2004-04-22 | — | — | US | claimed |
| WO-2004032875-A2 | PROCESS FOR THE PREPARATION OF TRI-NITROGEN CONTAINING HETEROARYL-DIAMINE DERIVATIVES USEFUL AS PHARMACEUTICAL AGENTS AND METHODS OF PRODUCING PHARMACEUTICAL AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-04-22 | — | — | WO | claimed |
| US-5459131-A | Renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1995-10-17 | — | — | US | claimed |
| US-5189023-A | Hypotensive agent | AMERICAN CYANAMID COMPANY (US) | 1993-02-23 | — | — | US | claimed |
| EP-0427939-A2 | Renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1991-05-22 | — | — | EP | claimed |
| EP-0376012-A2 | Renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1990-07-04 | — | — | EP | claimed |
| EP-0376040-A2 | N-phosphinyl di-and tripeptides as renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1990-07-04 | — | — | EP | claimed |
| US-20250313522-A1 | PHENOXY CARBOXYLIC ACID COMPOUNDS AND MEDICAL USES THEREOF | QINGDAO RISING BIOTECHNOLOGY CO., LTD (CN) | 2025-10-09 | — | — | US | disclosed |
| US-12365643-B2 | Phenoxy carboxylic acid compounds and medical uses thereof | QINGDAO RISING BIOTECHNOLOGY CO., LTD (CN) | 2025-07-22 | — | — | US | disclosed |
| US-20230331751-A1 | STEREOSELECTIVE MANUFACTURE OF SELECTED PURINE PHOSPHORAMIDATES | Atea Pharmaceuticals, Inc. (US) | 2023-10-19 | — | — | US | disclosed |
| CN-110857268-B | Phenoxy acid compound and medical application thereof | 青岛睿森生物科技有限公司 | 2022-10-04 | — | — | CN | disclosed |
| US-20220119333-A1 | PHENOXY ACID COMPOUNDS AND MEDICAL USES THEREOF | QINGDAO WHOLESOMTECH CO., LTD. (CN) | 2022-04-21 | — | — | US | disclosed |
| EP-3980057-A1 | METHODS OF PRODUCING SHIGA TOXIN B-SUBUNIT (STXB) MONOMERS AND OLIGOMERS, AND USES THEREOF | Institut Curie (FR) | 2022-04-13 | — | — | EP | disclosed |
| EP-0975689-A1 | CHEMICAL IMIDIZATION REAGENT FOR POLYIMIDE SYNTHESIS | Olin Microelectronic Chemicals, Inc. (US) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998046666-A1 | CHEMICAL IMIDIZATION REAGENT FOR POLYIMIDE SYNTHESIS | OLIN MICROELECTRONIC CHEMICALS, INC. (US) | 1998-10-22 | — | — | WO | disclosed |
| US-5789524-A | REACTING POLYAMIC ACID AND PHOSPHORAMIDE IN THE PRESENCE OF A BASE CATALYST | OLIN MICROELECTRONIC CHEMICALS, INC. (US) | 1998-08-04 | — | — | US | disclosed |
| US-5459131-A | Renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1995-10-17 | — | — | US | disclosed |
| US-5189023-A | Hypotensive agent | AMERICAN CYANAMID COMPANY (US) | 1993-02-23 | — | — | US | disclosed |
| EP-0473936-A1 | Renin Inhibitors | AMERICAN CYANAMID COMPANY (US) | 1992-03-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220119333-A1 | PHENOXY ACID COMPOUNDS AND MEDICAL USES THEREOF | PYGL, SLC10A1, GYS2 | TSHR 2406/4885NPSR1 668/4885RXFP1 1095/4885 |
| US-12365643-B2 | Phenoxy carboxylic acid compounds and medical uses thereof | PYGL, SLC10A1, GYS2 | TSHR 2525/4885NPSR1 914/4885RXFP1 1265/4885 |
| US-20040077878-A1 | Process for the preparation of tri-nitrogen containing heteroaryl-diamine derivatives useful as pharmaceutical agents and methods of producing pharmaceutical agents | IMPDH1, IMPDH2, HNMT | TSHR 658/4885NPSR1 221/4885RXFP1 2888/4885 |
| US-20230331751-A1 | STEREOSELECTIVE MANUFACTURE OF SELECTED PURINE PHOSPHORAMIDATES | NUDT1, PNP, ATIC | TSHR 3475/4885NPSR1 755/4885RXFP1 3363/4885 |
| US-20250313522-A1 | PHENOXY CARBOXYLIC ACID COMPOUNDS AND MEDICAL USES THEREOF | PYGL, SLC10A1, GYS2 | TSHR 2525/4885NPSR1 914/4885RXFP1 1265/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.