Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 7/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP2C18 | P33260 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 2/20 | 0.42 |
| ▸ | SOAT2 | O75908 | 2/20 | 0.41 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.41 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27676108 | 0.85 | SOAT2 (0.52) | CYP2C9POLBABCB1LMNACYP2C19 | |
| SCHEMBL9453146 | 0.84 | SOAT1 (0.58) | CYP2C9POLBABCB1LMNACYP2C19 | |
| SCHEMBL11086699 | 0.82 | SOAT1 (0.60) | CYP2C9LMNACYP2C19TSHRNFKB1 | |
| SCHEMBL14973857 | 0.74 | CYP2C9 (0.48) | CYP2C9POLBLMNACYP2C19CYP2C18 | |
| SCHEMBL3973316 | 0.72 | CYP2C9 (0.56) | CYP2C9POLBLMNACYP2C19CYP2C18 | |
| SCHEMBL5266895 | 0.72 | CYP2C9 (0.44) | CYP2C9LMNACYP2C19CYP2C18TSHR | |
| SCHEMBL20413716 | 0.72 | CYP2C9 (0.46) | CYP2C9POLBLMNACYP2C19CYP2C18 | |
| SCHEMBL3433504 | 0.71 | CYP2C9 (0.55) | CYP2C9POLBLMNACYP2C19CYP2C18 | |
| SCHEMBL4255883 | 0.71 | CYP2C9 (0.52) | CYP2C9POLBLMNACYP2C19CYP2C18 | |
| SCHEMBL27678180 | 0.71 | OXTR (0.44) | CYP2C9LMNACYP2C19TSHRNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4460773-A | ANTITUMOR AGENTS, VIRICIDES | LION CORPORATION (JP) | 1984-07-17 | — | — | US | disclosed |