Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.49 |
| ▸ | AURKA | O14965 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4641001 | 0.77 | MAPT (0.58) | MAPTALDH1A1GAARAB9ANPC1 | |
| SCHEMBL11400723 | 0.72 | ALDH1A1 (0.48) | MAPTALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL13562420 | 0.72 | MAPT (0.60) | MAPTALDH1A1GAARAB9ANPC1 | |
| SCHEMBL30119815 | 0.71 | MAPT (0.58) | MAPTALDH1A1GAARAB9ANPC1 | |
| SCHEMBL23413394 | 0.70 | MAPT (0.50) | MAPTALDH1A1GAARAB9ANPC1 | |
| SCHEMBL31484130 | 0.70 | MAPT (0.56) | MAPTALDH1A1GAARAB9ANPC1 | |
| SCHEMBL29887198 | 0.70 | MAPT (0.50) | MAPTALDH1A1GAARAB9ANPC1 | |
| SCHEMBL7982480 | 0.69 | MAPK10 (0.69) | MAPTALDH1A1GAARAB9ANPC1 | |
| SCHEMBL13689760 | 0.69 | KMT2A (0.66) | MAPTALDH1A1GAARAB9ANPC1 | |
| SCHEMBL29740043 | 0.69 | MAPT (0.65) | MAPTALDH1A1GAARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4460403-A | 2,3-Dicyano 6 phenyl pyrazine herbicides | KYOWA GAS CHEMICAL INDUSTRY CO., LTD. (JP) | 1984-07-17 | — | — | US | disclosed |
| US-4259489-A | PREEMERGENCE AND POSTEMERGENCE HERBICIDES | KYOWA GAS CHEMICAL INDUSTRY CO. LTD. (JP) | 1981-03-31 | — | — | US | disclosed |