Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.57 |
| ▸ | EGFR | P00533 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | PDGFRB | P09619 | 4/20 | 0.55 |
| ▸ | PDGFRA | P16234 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | AURKA | O14965 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1702666 | 0.81 | PDGFRB (0.50) | ALDH1A1NPC1RAB9AGAAEGFR | |
| SCHEMBL31620747 | 0.79 | NPC1 (0.65) | MAPTALDH1A1NPC1RAB9AGAA | |
| SCHEMBL4640142 | 0.78 | BRAF (0.64) | EGFRPOLBPDGFRBPDGFRAKMT2A | |
| SCHEMBL4640977 | 0.77 | PDGFRB (0.54) | MAPTALDH1A1NPC1RAB9AGAA | |
| SCHEMBL11090022 | 0.77 | MAPT (0.47) | MAPTALDH1A1NPC1RAB9AGAA | |
| SCHEMBL15256286 | 0.77 | PDGFRB (0.66) | MAPTALDH1A1NPC1RAB9AMAPK10 | |
| SCHEMBL11343230 | 0.77 | PDGFRB (0.61) | ALDH1A1NPC1RAB9AGAAEGFR | |
| SCHEMBL11088998 | 0.77 | MAPT (0.53) | MAPTALDH1A1NPC1RAB9AGAA | |
| SCHEMBL13562420 | 0.76 | MAPT (0.60) | MAPTALDH1A1NPC1RAB9AGAA | |
| SCHEMBL1857786 | 0.76 | PDGFRB (0.59) | ALDH1A1NPC1RAB9AGAAEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1267819-B1 | Quinoxaline derivatives, compositions containing them und use as UV-filter | MERCK PATENT GMBH (DE) | 2008-08-06 | — | — | EP | disclosed |
| US-20030207886-A1 | Preparation containing quinoxaline derivatives | MERCK PATENT GMBH (DE) | 2003-11-06 | — | — | US | disclosed |
| EP-1267819-A2 | PREPARATION CONTAINING QUINOXALINE DERIVATIVES | MERCK PATENT GmbH (DE) | 2003-01-02 | — | — | EP | disclosed |
| WO-2001068047-A2 | PREPARATION CONTAINING QUINOXALINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2001-09-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030207886-A1 | Preparation containing quinoxaline derivatives | CUTA, XPA, NQO2 | MAPT 2455/4885ALDH1A1 1898/4885NPC1 4650/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.