SCHEMBL11089018

SCHEMBL11089018

COc1ccc(CC(C)NCC(O)c2ccccc2O)c(OC)c1OC

nearest known ligand 0.53

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 10/20 0.53
ADRB1 P08588 7/20 0.43
ADRB3 P13945 7/20 0.43
KDM4E B2RXH2 2/20 0.41
ALDH1A1 P00352 1/20 0.38
TAAR1 Q96RJ0 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11089048 0.99 ADRB2 (0.52) ADRB2ADRB1ADRB3KDM4E
SCHEMBL7150274 0.85 ADRB2 (0.51) ADRB2ADRB1ADRB3
SCHEMBL7150271 0.85 ADRB2 (0.51) ADRB2ADRB1ADRB3
SCHEMBL11412158 0.83 ADRB2 (0.48) ADRB2ADRB1ADRB3KDM4EALDH1A1
SCHEMBL9816896 0.82 ADRB2 (0.48) ADRB2ADRB1ADRB3
Hydrochloric Acid SCHEMBL11080706 0.82 ADRB2 (0.47) ADRB2ADRB1ADRB3KDM4EALDH1A1
SCHEMBL11431797 0.80 ALDH1A1 (0.49) ADRB2ADRB1KDM4EALDH1A1TAAR1
SCHEMBL7148275 0.80 ADRB1 (0.51) ADRB2ADRB1ADRB3
SCHEMBL7148280 0.80 ADRB1 (0.51) ADRB2ADRB1ADRB3
SCHEMBL11088831 0.80 ADRB1 (0.51) ADRB2ADRB1ADRB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4490392-A Benzylalcohol derivative and process for preparing TANABE SEIYAKU CO., LTD. (JP) 1984-12-25 US claimed