SCHEMBL11089170

SCHEMBL11089170

Cc1cc(C)c(C)c(Oc2ccc(N)cc2)c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.60
SMN1; SMN2 Q16637 3/20 0.60
TEAD4 Q15561 1/20 0.53
MAPT P10636 4/20 0.52
TDP1 Q9NUW8 3/20 0.52
POLB P06746 1/20 0.52
CYP3A4 P08684 1/20 0.46
TSHR P16473 1/20 0.46
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
MITF O75030 1/20 0.42
GAA P10253 1/20 0.42
GFER P55789 1/20 0.42
NLRP1 Q9C000 1/20 0.42
NOD2 Q9HC29 1/20 0.42
MAOA P21397 2/20 0.41
MAPK1 P28482 2/20 0.40
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
HPGD P15428 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31448066 1.00 ALDH1A1 (0.60) ALDH1A1SMN1; SMN2TEAD4MAPTTDP1
SCHEMBL9487744 0.82 ALDH1A1 (0.43) ALDH1A1SMN1; SMN2MAPTTDP1POLB
SCHEMBL9488025 0.81 LTA4H (0.42) ALDH1A1SMN1; SMN2CYP3A4TSHRMEN1
SCHEMBL31448173 0.81 ALDH1A1 (0.38) ALDH1A1SMN1; SMN2TEAD4MAPTPOLB
Hydrochloric Acid SCHEMBL31447977 0.80 ALDH1A1 (0.37) ALDH1A1SMN1; SMN2MAPTTDP1POLB
SCHEMBL11528953 0.79 TEAD4 (0.61) ALDH1A1SMN1; SMN2TEAD4MAPTTDP1
SCHEMBL9321941 0.79 ALDH1A1 (0.67) ALDH1A1SMN1; SMN2TEAD4MAPTTDP1
SCHEMBL29475151 0.78 ALDH1A1 (0.50) ALDH1A1SMN1; SMN2TEAD4MAPTTDP1
SCHEMBL1352574 0.78 ALDH1A1 (0.50) ALDH1A1SMN1; SMN2TEAD4MAPTTDP1
SCHEMBL15945517 0.77 TEAD4 (0.58) ALDH1A1SMN1; SMN2TEAD4MAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112368330-B Thermoplastic resin composition and method for producing same 大金工业株式会社 2023-03-21 CN claimed
CN-112368330-B Thermoplastic resin composition and method for producing same 大金工业株式会社 2023-03-21 CN disclosed
CN-111770963-B Thermoplastic resin composition and method for producing same 大金工业株式会社 2022-06-28 CN disclosed
CN-112368330-A Thermoplastic resin composition and method for producing same 大金工业株式会社 2021-02-12 CN disclosed
CN-111770963-A Thermoplastic resin composition and method for producing same 大金工业株式会社 2020-10-13 CN disclosed
EP-0113922-A2 Process for the manufacture of cationic methine dyes BAYER AG (DE) 1984-07-25 EP disclosed
EP-0113920-A2 Process for the manufacture of stable solutions of cationic methine dyes, and their use in spin dyeing BAYER AG (DE) 1984-07-25 EP disclosed
EP-0113921-A2 Process for the manufacture of stable solutions of cationic methine dyes BAYER AG (DE) 1984-07-25 EP disclosed
US-3956264-A Basic azo dyestuffs having indolyl-methyleneamino substituent in the diazo component BAYER AKTIENGESELLSCHAFT (DT) 1976-05-11 US disclosed