Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | FABP7 | O15540 | 1/20 | 0.33 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.33 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25604498 | 0.78 | CA1 (0.43) | — | |
| SCHEMBL1573266 | 0.77 | FABP7 (0.38) | MTNR1AMTNR1BFABP7FABP5 | |
| SCHEMBL11076711 | 0.76 | LMNA (0.38) | CYP1A2CYP2C19LMNAALDH1A1POLB | |
| SCHEMBL11076708 | 0.76 | LMNA (0.38) | CYP1A2CYP2C19LMNAALDH1A1POLB | |
| SCHEMBL11076717 | 0.76 | LMNA (0.38) | CYP1A2CYP2C19LMNAALDH1A1POLB | |
| SCHEMBL25604514 | 0.75 | MTNR1A (0.53) | CYP1A2CYP2C9MTNR1AMTNR1BFABP7 | |
| SCHEMBL25604499 | 0.75 | MTNR1A (0.41) | CYP1A2CYP3A4CYP2C9LMNAALDH1A1 | |
| SCHEMBL1196934 | 0.75 | FABP7 (0.50) | NOTUMPOLBMTNR1AMTNR1BGABRA1 | |
| SCHEMBL30493000 | 0.75 | FABP7 (0.50) | NOTUMPOLBMTNR1AMTNR1BGABRA1 | |
| SCHEMBL20925930 | 0.74 | MAPK1 (0.39) | NOTUMCYP1A2CYP2C19ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4442296-A | LARVICIDES | FMC CORPORATION (US) | 1984-04-10 | — | — | US | disclosed |
| US-4408057-A | 4-Heterocyclic-substituted-2-indanyl alcohols and insecticidal ester derivatives | FMC CORPORATION (US) | 1983-10-04 | — | — | US | disclosed |
| US-4368205-A | 4-Heterocyclic-substituted-2-indanyl alcohols and insecticidal ester derivatives | FMC CORPORATION (US) | 1983-01-11 | — | — | US | disclosed |