Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.54 |
| ▸ | CHUK | O15111 | 1/20 | 0.53 |
| ▸ | KIF11 | P52732 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.45 |
| ▸ | LCK | P06239 | 1/20 | 0.45 |
| ▸ | CSF1R | P07333 | 1/20 | 0.45 |
| ▸ | PIM1 | P11309 | 1/20 | 0.45 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.45 |
| ▸ | FLT3 | P36888 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL64307 | 0.87 | PARP1 (0.61) | PDE10AKIF11PARP1CA12CA9 | |
| SCHEMBL29409549 | 0.87 | PARP1 (0.61) | PDE10AKIF11PARP1CA12CA9 | |
| SCHEMBL29683700 | 0.87 | PARP1 (0.61) | PDE10AKIF11PARP1CA12CA9 | |
| SCHEMBL29453525 | 0.87 | CHUK (0.64) | CHUKPARP1LMNACYP1A2GAA | |
| SCHEMBL607827 | 0.87 | CHUK (0.64) | CHUKPARP1LMNACYP1A2GAA | |
| SCHEMBL22394444 | 0.84 | PARP1 (0.59) | PDE10AKIF11PARP1CA12CA9 | |
| SCHEMBL550449 | 0.82 | CHUK (0.60) | CHUKPARP1LMNACYP1A2GAA | |
| SCHEMBL5914553 | 0.78 | KIF11 (0.68) | PDE10AKIF11PARP1CA12CA9 | |
| SCHEMBL30975189 | 0.78 | KIF11 (0.68) | PDE10AKIF11PARP1CA12CA9 | |
| SCHEMBL607394 | 0.77 | AHR (0.64) | CHUKKIF11LMNAHPGDCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0037563-B1 | SULFUR DYES OF THE CARBAZOLE SERIES, THEIR PREPARATION AND APPLICATION, AS WELL AS INTERMEDIATE COMPOUNDS | CASSELLA Aktiengesellschaft (DE) | 1984-02-15 | — | — | EP | disclosed |
| US-4360459-A | Sulphur dyestuffs of the carbazole series | CASSELLA AKTIENGESELLSCHAFT (DE) | 1982-11-23 | — | — | US | disclosed |
| EP-0037563-A1 | Sulfur dyes of the carbazole series, their preparation and application, as well as intermediate compounds | CASSELLA Aktiengesellschaft (DE) | 1981-10-14 | — | — | EP | disclosed |