SCHEMBL64307

SCHEMBL64307

Nc1ccc2[nH]c3ccc(N)cc3c2c1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 2/20 0.61
KIF11 P52732 2/20 0.60
CA12 O43570 1/20 0.52
CA9 Q16790 1/20 0.52
AR P10275 1/20 0.50
NGFR P08138 1/20 0.50
CDK4 P11802 1/20 0.50
CCND1 P24385 1/20 0.50
CYP2A6 P11509 1/20 0.46
KEAP1 Q14145 1/20 0.46
PDE10A Q9Y233 1/20 0.46
KDM4E B2RXH2 1/20 0.44
MEN1 O00255 1/20 0.44
ALDH1A1 P00352 1/20 0.44
MAPT P10636 1/20 0.44
TSHR P16473 1/20 0.44
GFER P55789 1/20 0.44
KMT2A Q03164 1/20 0.44
HSD17B10 Q99714 1/20 0.44
AHR P35869 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29409549 1.00 PARP1 (0.61) PARP1KIF11CA12CA9AR
SCHEMBL29683700 1.00 PARP1 (0.61) PARP1KIF11CA12CA9AR
SCHEMBL22394444 0.97 PARP1 (0.59) PARP1KIF11CA12CA9AR
SCHEMBL30975189 0.91 KIF11 (0.68) PARP1KIF11CA12CA9AR
SCHEMBL5914553 0.91 KIF11 (0.68) PARP1KIF11CA12CA9AR
SCHEMBL30337091 0.89 PARP1 (0.67) PARP1KIF11CDK4CCND1KDM4E
SCHEMBL29565567 0.89 PARP1 (0.67) PARP1KIF11CDK4CCND1KDM4E
SCHEMBL29483487 0.89 PARP1 (0.67) PARP1KIF11CDK4CCND1KDM4E
Carbazole SCHEMBL28862120 0.89 PARP1 (0.67) PARP1KIF11CDK4CCND1KDM4E
SCHEMBL274921 0.89 PARP1 (0.67) PARP1KIF11CDK4CCND1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1245 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12628491-B2 Organic-inorganic adhesion layer and its use in perovskite solar cells and modules Tandem PV (US) 2026-05-12 US claimed
CN-117946355-B Preparation method and application of asymmetric self-supporting covalent organic framework film 中国科学技术大学 2024-06-18 CN claimed
CN-118126325-A Low-temperature-cured alkali-soluble photosensitive resin and preparation method thereof 深圳先进电子材料国际创新研究院 2024-06-04 CN claimed
CN-117946355-A Preparation method and application of asymmetric self-supporting covalent organic framework film 中国科学技术大学 2024-04-30 CN claimed
CN-117940842-A Liquid crystal aligning agent, liquid crystal alignment film, method for manufacturing liquid crystal display element, and liquid crystal display element 日产化学株式会社 2024-04-26 CN claimed
CN-117916657-A Liquid crystal aligning agent, liquid crystal alignment film, method for manufacturing liquid crystal display element, and liquid crystal display element 日产化学株式会社 2024-04-19 CN claimed
WO-2024081751-A1 ORGANIC-INORGANIC ADHESION LAYER AND ITS USE IN PEROVSKITE SOLAR CELLS AND MODULES Tandem PV (US) 2024-04-18 WO claimed
US-20240121970-A1 ORGANIC-INORGANIC ADHESION LAYER AND ITS USE IN PEROVSKITE SOLAR CELLS AND MODULES Tandem PV 2024-04-11 US claimed
CN-117700770-A COF material, COF-based heterostructure catalyst, and preparation method and application thereof 淮安中顺环保科技有限公司 2024-03-15 CN claimed
WO-2024046225-A1 ESTER TYPE PHOTOSENSITIVE POLYIMIDE COMPOSITE MATERIAL, PREPARATION METHOD AND SEMICONDUCTOR APPARATUS 深圳先进电子材料国际创新研究院 2024-03-07 WO claimed
US-20110152558-A1 PROCESS FOR PRODUCING DIARYL CARBONATES CHINA PETROCHEMICAL DEVELOPMENT CORPORATION (TW) 2011-06-23 US claimed
US-20090274970-A1 CARBAZOLE CONTAINING CHARGE TRANSPORT LAYER PHOTOCONDUCTORS XEROX CORPORATION (US) 2009-11-05 US claimed
US-20080098535-A1 Keratin Dyeing Compounds, Keratin Dyeing Compositions Containing Them, And Use Thereof GLENN ROBERT W JR 2008-05-01 US claimed
CN-100343740-C Aligning agent for liquid crystal and liquid-crystal display element NISSAN CHEMICAL IND LTD (JP) 2007-10-17 CN claimed
US-20060024452-A1 Aligning agent for liquid crystal and liquid-crystal display element NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2006-02-02 US claimed
CN-1685282-A Aligning agent for liquid crystal and liquid-crystal display element NISSAN CHEMICAL IND LTD (JP) 2005-10-19 CN claimed
US-20050217038-A1 Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof PROCTER & GAMBLE COMPANY, THE 2005-10-06 US claimed
EP-0577245-B1 Photogenerating azo pigments XEROX CORP (US) 1998-12-02 EP claimed
US-5281503-A Multilayer element with disazo pigments and charge generating layer XEROX CORPORATION (US) 1994-01-25 US claimed
EP-0577245-A1 Photogenerating azo pigments XEROX CORPORATION (US) 1994-01-05 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050217038-A1 Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof KRT18, CKMT1A; CKMT1B, TUBB6 PARP1 2050/4885KIF11 779/4885CA12 685/4885
US-20080098535-A1 Keratin Dyeing Compounds, Keratin Dyeing Compositions Containing Them, And Use Thereof KRT18, CKMT1A; CKMT1B, TUBB6 PARP1 2050/4885KIF11 779/4885CA12 685/4885
US-20110152558-A1 PROCESS FOR PRODUCING DIARYL CARBONATES CA2, POR, CBR3 PARP1 3056/4885KIF11 4130/4885CA12 22/4885
US-12628491-B2 Organic-inorganic adhesion layer and its use in perovskite solar cells and modules EPCAM, CDH1, L1CAM PARP1 1529/4885KIF11 1474/4885CA12 186/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.