Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.49 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11088612 | 0.91 | LMNA (0.48) | KDM4EHSD17B10TSHRMAPK10ALDH1A1 | |
| SCHEMBL11092677 | 0.88 | KDM4E (0.53) | KDM4EHSD17B10TSHRMAPK10ALDH1A1 | |
| SCHEMBL11130485 | 0.83 | KDM4E (0.47) | KDM4EHSD17B10TSHRMAPK10ALDH1A1 | |
| SCHEMBL11131710 | 0.80 | KDM4E (0.50) | KDM4EHSD17B10TSHRALDH1A1RAB9A | |
| SCHEMBL11090510 | 0.79 | PDGFRB (0.55) | KDM4EHSD17B10TSHRALDH1A1RAB9A | |
| SCHEMBL11091891 | 0.75 | LMNA (0.55) | KDM4EHSD17B10TSHRMAPK10ALDH1A1 | |
| SCHEMBL4156930 | 0.75 | PDGFRB (0.64) | KDM4EHSD17B10ALDH1A1PDGFRBPDGFRA | |
| SCHEMBL11090756 | 0.74 | KDM4E (0.43) | KDM4EHSD17B10TSHRALDH1A1RAB9A | |
| SCHEMBL11093811 | 0.74 | MAPT (0.56) | KDM4EHSD17B10TSHRALDH1A1RAB9A | |
| SCHEMBL11091553 | 0.74 | MAPT (0.49) | KDM4EHSD17B10RAB9ANPC1PDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4460773-A | ANTITUMOR AGENTS, VIRICIDES | LION CORPORATION (JP) | 1984-07-17 | — | — | US | disclosed |