Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.43 |
| ▸ | RELA | Q04206 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.40 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PDE5A | O76074 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11130485 | 0.81 | KDM4E (0.47) | KDM4ERAB9AALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL11089283 | 0.74 | KDM4E (0.54) | KDM4ERAB9AALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL11084613 | 0.73 | NR3C1 (0.45) | KDM4ERAB9AALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL11131710 | 0.73 | KDM4E (0.50) | KDM4ERAB9AALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL11090510 | 0.70 | PDGFRB (0.55) | KDM4ERAB9AALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL11088612 | 0.70 | LMNA (0.48) | KDM4ERAB9AALDH1A1NPC1HPGD | |
| SCHEMBL11092677 | 0.70 | KDM4E (0.53) | KDM4ERAB9AALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL11092417 | 0.69 | PDE5A (0.43) | KDM4ERAB9AALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL11089081 | 0.69 | MAPT (0.59) | KDM4EALDH1A1SMN1; SMN2HPGDLMNA | |
| SCHEMBL11091891 | 0.69 | LMNA (0.55) | KDM4ERAB9AALDH1A1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4460773-A | ANTITUMOR AGENTS, VIRICIDES | LION CORPORATION (JP) | 1984-07-17 | — | — | US | disclosed |