Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 10/20 | 0.40 |
| ▸ | CNR2 | P34972 | 9/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10472797 | 0.91 | PTGS2 (0.63) | PTGS2CA1CA2CA9CNR1 | |
| SCHEMBL10474113 | 0.91 | PTGS2 (0.63) | PTGS2CYP19A1CA1CA2CA9 | |
| SCHEMBL10473733 | 0.91 | PTGS2 (0.63) | PTGS2CA1CA2CA9CNR1 | |
| SCHEMBL15285314 | 0.85 | PTGS2 (0.57) | PTGS2CYP19A1CA1CA2CA9 | |
| SCHEMBL31185803 | 0.79 | PTGS2 (0.73) | PTGS2CYP19A1CA1CA2CA9 | |
| SCHEMBL31185907 | 0.79 | PTGS2 (0.73) | PTGS2CYP19A1CA1CA2CA9 | |
| SCHEMBL31185832 | 0.79 | PTGS2 (0.73) | PTGS2CYP19A1CA1CA2CA9 | |
| SCHEMBL18586439 | 0.79 | PTGS2 (0.73) | PTGS2CYP19A1CA1CA2CA9 | |
| SCHEMBL20098971 | 0.78 | CYP19A1 (0.56) | PTGS2CYP19A1 | |
| SCHEMBL30380963 | 0.78 | CYP19A1 (0.56) | PTGS2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4473704-A | ANALGESICS, ANTIEMETICS | PFIZER INC. (US) | 1984-09-25 | — | — | US | disclosed |