Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERBB2 | P04626 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.41 |
| ▸ | HPGD | P15428 | 9/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.41 |
| ▸ | RAB9A | P51151 | 6/20 | 0.41 |
| ▸ | GAA | P10253 | 6/20 | 0.41 |
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.38 |
| ▸ | USP8 | P40818 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11089932 | 0.90 | ERBB2 (0.47) | ERBB2KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL11093965 | 0.87 | KDM4E (0.50) | ERBB2KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL11402185 | 0.85 | KDM4E (0.59) | ERBB2KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL11096062 | 0.84 | CTSS (0.44) | KDM4EALDH1A1HPGDSMN1; SMN2RAB9A | |
| SCHEMBL11090728 | 0.79 | CTSS (0.46) | KDM4EALDH1A1HPGDSMN1; SMN2GAA | |
| SCHEMBL2681245 | 0.78 | ERBB2 (0.61) | ERBB2KDM4EALDH1A1HPGDRAB9A | |
| SCHEMBL11087127 | 0.78 | ADORA1 (0.51) | KDM4EALDH1A1HPGDSMN1; SMN2RAB9A | |
| SCHEMBL11094919 | 0.78 | ADORA1 (0.45) | KDM4EALDH1A1HPGDSMN1; SMN2GAA | |
| SCHEMBL11090104 | 0.76 | ADORA1 (0.59) | ERBB2KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL11085923 | 0.73 | CTSS (0.47) | KDM4EALDH1A1HPGDSMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4460403-A | 2,3-Dicyano 6 phenyl pyrazine herbicides | KYOWA GAS CHEMICAL INDUSTRY CO., LTD. (JP) | 1984-07-17 | — | — | US | disclosed |
| US-4259489-A | PREEMERGENCE AND POSTEMERGENCE HERBICIDES | KYOWA GAS CHEMICAL INDUSTRY CO. LTD. (JP) | 1981-03-31 | — | — | US | disclosed |