Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 10/20 | 0.59 |
| ▸ | ADORA2A | P29274 | 9/20 | 0.59 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.49 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.47 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.47 |
| ▸ | FLT1 | P17948 | 1/20 | 0.47 |
| ▸ | GRK5 | P34947 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.47 |
| ▸ | CDK8 | P49336 | 1/20 | 0.47 |
| ▸ | GSK3A | P49840 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | PRKX | P51817 | 1/20 | 0.47 |
| ▸ | NEK2 | P51955 | 1/20 | 0.47 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.47 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.47 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.47 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11093965 | 0.89 | KDM4E (0.50) | ADORA1ADORA2AADORA2BCHEK1ABL1 | |
| SCHEMBL11089932 | 0.86 | ERBB2 (0.47) | ADORA1ADORA2AADORA2BERBB2KMT2A | |
| SCHEMBL11093505 | 0.85 | ADORA1 (0.49) | ADORA1ADORA2AADORA2BCHEK1ABL1 | |
| SCHEMBL11085923 | 0.84 | CTSS (0.47) | ADORA1ADORA2AADORA2BMAPK14KMT2A | |
| SCHEMBL11090534 | 0.84 | CTSS (0.49) | ADORA1ADORA2AADORA2BKMT2AMEN1 | |
| SCHEMBL11090451 | 0.83 | MAP4K4 (0.48) | ADORA1ADORA2AADORA2BABL1LRRK2 | |
| SCHEMBL11093293 | 0.83 | ADORA1 (0.60) | ADORA1ADORA2AADORA2BKMT2AKDM4E | |
| SCHEMBL11403379 | 0.82 | L3MBTL1 (0.54) | ADORA1ADORA2ACHEK1ABL1PDGFRB | |
| SCHEMBL7537686 | 0.78 | ERBB2 (0.59) | ADORA1ADORA2ACHEK1ABL1PDGFRB | |
| SCHEMBL11084595 | 0.78 | ALDH1A1 (0.51) | ADORA1ADORA2ACHEK1ABL1PDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4460403-A | 2,3-Dicyano 6 phenyl pyrazine herbicides | KYOWA GAS CHEMICAL INDUSTRY CO., LTD. (JP) | 1984-07-17 | — | — | US | disclosed |
| US-4259489-A | PREEMERGENCE AND POSTEMERGENCE HERBICIDES | KYOWA GAS CHEMICAL INDUSTRY CO. LTD. (JP) | 1981-03-31 | — | — | US | disclosed |