Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11085155 | 0.88 | MEN1 (0.36) | MEN1KMT2AKDM4ETSHRHTT | |
| SCHEMBL11084255 | 0.88 | SSTR3 (0.37) | MEN1KMT2AKDM4ETSHRHTT | |
| SCHEMBL11085850 | 0.86 | CA1 (0.40) | CA1CA2CA4CA6MEN1 | |
| SCHEMBL11086889 | 0.86 | SSTR3 (0.37) | MEN1KMT2AKDM4ETSHRHTT | |
| SCHEMBL11084665 | 0.85 | HTR2A (0.39) | MEN1KMT2AKDM4ETSHRHTT | |
| SCHEMBL11092628 | 0.83 | DRD2 (0.41) | MEN1KMT2AKDM4ETSHRHTT | |
| SCHEMBL11085886 | 0.82 | PDE5A (0.36) | MEN1KMT2AKDM4ETSHRHTT | |
| SCHEMBL11081951 | 0.82 | ESR1 (0.40) | MEN1KMT2AALDH1A1ESR1PGR | |
| SCHEMBL11089317 | 0.81 | MEN1 (0.35) | MEN1KMT2AKDM4ETSHRHTT | |
| SCHEMBL11093337 | 0.80 | HTR7 (0.43) | MEN1KMT2AKDM4ETSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0115607-A1 | Tetrahydrocarbazol derivatives | MERCK PATENT GmbH (DE) | 1984-08-15 | — | — | EP | disclosed |