Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 6/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ACACB | O00763 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10300053 | 0.79 | ALDH1A1 (0.65) | APPALDH1A1MAPTACACBTSHR | |
| SCHEMBL770159 | 0.79 | ALDH1A1 (0.65) | APPALDH1A1MAPTACACBTSHR | |
| SCHEMBL9073927 | 0.76 | APP (0.68) | APPALDH1A1HPGDMAPTALOX15 | |
| SCHEMBL20089259 | 0.76 | VCP (0.55) | ALDH1A1HPGDACACBNPSR1RAB9A | |
| SCHEMBL8063434 | 0.75 | CYP2A6 (0.48) | APPALDH1A1HPGDMAPTACACB | |
| SCHEMBL28972857 | 0.73 | APP (0.69) | APPALDH1A1HPGDMAPTACACB | |
| SCHEMBL31542885 | 0.73 | MEN1 (0.59) | APPALDH1A1HPGDMAPTACACB | |
| SCHEMBL8028758 | 0.73 | ALDH1A1 (0.55) | APPALDH1A1MAPTACACBTSHR | |
| SCHEMBL9130686 | 0.72 | APP (0.68) | APPALDH1A1HPGDMAPTALOX15 | |
| SCHEMBL30363617 | 0.72 | APP (0.53) | APPALDH1A1HPGDMAPTACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4431586-A | Monocyclic telluropyrones | EASTMAN KODAK COMPANY (US) | 1984-02-14 | — | — | US | disclosed |