SCHEMBL11089557

SCHEMBL11089557

[c]1ccccc1-c1cccc2ocnc12

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
NR4A2 P43354 1/20 0.33
DHODH Q02127 1/20 0.33
EPHB4 P54760 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1365239 0.78 NR4A2 (0.39) NR4A2DHODHEPHB4
SCHEMBL1884974 0.74 NR4A2 (0.43) NR4A2DHODH
SCHEMBL27527824 0.71 TOP2A (0.42) NR4A2DHODH
SCHEMBL12637430 0.71 NPC1 (0.40) NR4A2DHODH
SCHEMBL12637425 0.71 NR4A2 (0.42) NR4A2DHODH
SCHEMBL713926 0.70 KDM4E (0.50)
SCHEMBL15511526 0.70 MAPT (0.46)
SCHEMBL28275604 0.70 MAOA (0.39)
SCHEMBL12637424 0.70 MAPT (0.45)
SCHEMBL27937978 0.70 KDM4E (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0044009-B1 PROCESS FOR THE PREPARATION OF 2-(2,2,2,-TRICHLORO-1-HYDROXY-ETHYL) PHENOLS BAYER AG (DE) 1984-09-26 EP disclosed
EP-0044009-A2 Process for the preparation of 2-(2,2,2,-Trichloro-1-hydroxy-ethyl) phenols BAYER AG (DE) 1982-01-20 EP disclosed