Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | THRB | P10828 | 2/20 | 0.53 |
| ▸ | GMNN | O75496 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | CES1 | P23141 | 5/20 | 0.47 |
| ▸ | FAAH | O00519 | 4/20 | 0.47 |
| ▸ | PLA2G6 | O60733 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL11080592 | 0.91 | CES2 (0.50) | CES2HSD17B10THRBGMNNTP53 | |
| SCHEMBL11274493 | 0.80 | CES1 (0.48) | CES2HSD17B10THRBGMNNTP53 | |
| SCHEMBL10491282 | 0.78 | HSD17B10 (0.63) | CES2HSD17B10THRBGMNNTP53 | |
| SCHEMBL6847376 | 0.78 | HSD17B10 (0.63) | CES2HSD17B10THRBGMNNTP53 | |
| SCHEMBL11144043 | 0.75 | CES2 (0.58) | CES2HSD17B10THRBGMNNTP53 | |
| Ethylene Glycol SCHEMBL1181201 | 0.72 | LMNA (0.55) | CES2HSD17B10THRBGMNNTP53 | |
| Ethylene Glycol SCHEMBL11211643 | 0.72 | LMNA (0.55) | CES2HSD17B10THRBGMNNTP53 | |
| SCHEMBL26982673 | 0.72 | CES2 (0.54) | CES2HSD17B10THRBGMNNTP53 | |
| SCHEMBL24370114 | 0.71 | THRB (0.57) | CES2HSD17B10THRBGMNNTP53 | |
| SCHEMBL9580049 | 0.71 | THRB (0.57) | CES2HSD17B10THRBGMNNTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0050327-B1 | PHOSPHOLIPIDS THAT CONTAIN SULPHUR, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THESE COMPOUNDS | Roche Diagnostics GmbH (DE) | 1984-06-20 | — | — | EP | disclosed |
| US-4444766-A | ANTITUMOR | BOEHRINGER MANNHEIM GMBH (DE) | 1984-04-24 | — | — | US | disclosed |
| EP-0050327-A1 | Phospholipids that contain sulphur, process for their preparation and medicines containing these compounds | Roche Diagnostics GmbH (DE) | 1982-04-28 | — | — | EP | disclosed |