Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | FAAH | O00519 | 2/20 | 0.46 |
| ▸ | MGLL | Q99685 | 2/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.44 |
| ▸ | CES2 | O00748 | 3/20 | 0.42 |
| ▸ | CES1 | P23141 | 3/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10824159 | 0.91 | LMNA (0.49) | LMNAALDH1A1GAASMN1; SMN2FAAH | |
| SCHEMBL14321564 | 0.79 | ALDH1A1 (0.53) | LMNAALDH1A1GAASMN1; SMN2FAAH | |
| SCHEMBL1608161 | 0.79 | ALDH1A1 (0.61) | LMNAALDH1A1GAASMN1; SMN2FAAH | |
| SCHEMBL28469425 | 0.75 | LMNA (0.71) | LMNAALDH1A1GAASMN1; SMN2FAAH | |
| SCHEMBL8123424 | 0.75 | CYP1A2 (0.45) | ALDH1A1GAASMN1; SMN2CYP19A1MAPT | |
| SCHEMBL11365025 | 0.71 | LMNA (0.64) | LMNAALDH1A1GAASMN1; SMN2FAAH | |
| SCHEMBL11365029 | 0.71 | LMNA (0.64) | LMNAALDH1A1GAASMN1; SMN2FAAH | |
| SCHEMBL10529985 | 0.70 | CYP19A1 (0.61) | LMNAALDH1A1GAASMN1; SMN2PDE4B | |
| SCHEMBL11232470 | 0.69 | ALDH1A1 (0.50) | LMNAALDH1A1GAASMN1; SMN2FAAH | |
| SCHEMBL11232464 | 0.69 | ALDH1A1 (0.50) | LMNAALDH1A1GAASMN1; SMN2FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435411-A | Combating fungi with 1-phenyl-2-(1,2,4-triazol-1-yl)-prop-2-en-1-ones | BAYER AKTIENGESELLSCHAFT (DE) | 1984-03-06 | — | — | US | claimed |
| US-4435411-A | Combating fungi with 1-phenyl-2-(1,2,4-triazol-1-yl)-prop-2-en-1-ones | BAYER AKTIENGESELLSCHAFT (DE) | 1984-03-06 | — | — | US | disclosed |
| US-4435411-A | Combating fungi with 1-phenyl-2-(1,2,4-triazol-1-yl)-prop-2-en-1-ones | BAYER AKTIENGESELLSCHAFT (DE) | 1984-03-06 | — | — | US | disclosed |