Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.56 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.56 |
| ▸ | NAMPT | P43490 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HPN | P05981 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8127981 | 0.97 | EPHX2 (0.59) | EPHX2NR1H4NAMPTL3MBTL1HDAC1 | |
| SCHEMBL3180689 | 0.87 | L3MBTL1 (0.61) | NAMPTL3MBTL1HDAC1GAACA1 | |
| SCHEMBL8203403 | 0.85 | NAMPT (0.54) | EPHX2NR1H4NAMPTL3MBTL1HDAC1 | |
| SCHEMBL133327 | 0.84 | KMT2A (0.60) | EPHX2NR1H4NAMPTL3MBTL1HDAC1 | |
| SCHEMBL10165179 | 0.84 | NAMPT (0.56) | EPHX2NR1H4NAMPTL3MBTL1HDAC1 | |
| SCHEMBL15259134 | 0.84 | L3MBTL1 (0.56) | NAMPTL3MBTL1HDAC1GAACA1 | |
| SCHEMBL8220824 | 0.83 | EPHX2 (0.60) | EPHX2NR1H4NAMPTL3MBTL1HDAC1 | |
| SCHEMBL1206337 | 0.83 | NAMPT (0.55) | EPHX2NR1H4NAMPTL3MBTL1HDAC1 | |
| SCHEMBL21119732 | 0.83 | NAMPT (0.55) | EPHX2NR1H4NAMPTL3MBTL1HDAC1 | |
| SCHEMBL3557570 | 0.83 | NAMPT (0.55) | EPHX2NR1H4NAMPTL3MBTL1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4464366-A | Cephem compounds having a terminal aminocarboxylic acid grouping and containing an azacyclyl(thio)ureido group | CIBA GEIGY CORPORATION (US) | 1984-08-07 | — | — | US | disclosed |