Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SDCBP | O00560 | 1/20 | 0.45 |
| ▸ | SDC2 | P34741 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL133327 | 0.88 | KMT2A (0.60) | NAMPTHDAC1L3MBTL1GAACA1 | |
| SCHEMBL3180689 | 0.87 | L3MBTL1 (0.61) | NAMPTHDAC1L3MBTL1GAACA1 | |
| SCHEMBL5736115 | 0.85 | HDAC1 (0.60) | NAMPTHDAC1L3MBTL1HDAC6HDAC10 | |
| SCHEMBL12511497 | 0.85 | CA2 (0.52) | NAMPTGAACA1CA2KMT2A | |
| Ethylene SCHEMBL11089909 | 0.85 | EPHX2 (0.56) | NAMPTHDAC1L3MBTL1GAACA1 | |
| SCHEMBL2874913 | 0.85 | NAMPT (0.54) | NAMPTHDAC1L3MBTL1GAACA1 | |
| SCHEMBL10165179 | 0.84 | NAMPT (0.56) | NAMPTHDAC1L3MBTL1GAACA1 | |
| SCHEMBL8127981 | 0.84 | EPHX2 (0.59) | NAMPTHDAC1L3MBTL1GAACA1 | |
| SCHEMBL23959162 | 0.84 | HDAC1 (0.61) | NAMPTHDAC1L3MBTL1GAAHDAC6 | |
| SCHEMBL12133585 | 0.84 | HDAC1 (0.58) | NAMPTHDAC1L3MBTL1GAACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008040934-A1 | HDAC INHIBITORS | CHROMA THERAPEUTICS LTD. (GB) | 2008-04-10 | — | — | WO | disclosed |