SCHEMBL1109013

SCHEMBL1109013

COc1nc(OC)nc(OC(C)=O)n1

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 2/20 0.42
MAPT P10636 1/20 0.42
HTT P42858 1/20 0.42
LMNA P02545 3/20 0.39
TDP1 Q9NUW8 1/20 0.39
CYP1A2 P05177 2/20 0.38
TNFSF11 O14788 1/20 0.38
ALDH1A1 P00352 3/20 0.37
F2 P00734 1/20 0.37
GLA P06280 1/20 0.37
HPGD P15428 1/20 0.37
BACE1 P56817 1/20 0.33
TSHR P16473 1/20 0.33
GAA P10253 1/20 0.33
ADORA2A P29274 1/20 0.32
ADORA1 P30542 1/20 0.32
ABCB11 O95342 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1500435 0.89 LMNA (0.39) NPSR1MAPTHTTLMNATDP1
SCHEMBL11587654 0.80 CYP3A4 (0.33) MAPTLMNAALDH1A1F2GLA
SCHEMBL11690916 0.76 POLB (0.32) NPSR1MAPTLMNA
SCHEMBL9371729 0.76 LMNA (0.38) NPSR1MAPTHTTLMNATDP1
SCHEMBL3075874 0.75 CYP3A4 (0.33) MAPTLMNAALDH1A1F2GLA
SCHEMBL23964443 0.75 ELANE (0.41) NPSR1MAPTHTTLMNATDP1
SCHEMBL22404886 0.75 SMN1; SMN2 (0.37) NPSR1MAPTHTTLMNATDP1
SCHEMBL33145 0.74 ALDH1A1 (0.43) NPSR1MAPTHTTLMNATDP1
SCHEMBL29286020 0.73 LMNA (0.44) LMNACYP1A2GAA
SCHEMBL22428980 0.73 MAPT (0.49) NPSR1MAPTHTTLMNATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230340165-A1 CROSS-LYNKED HYALURONIC ACID SYNTHESIS PROCESS ISTITUTO GANASSINI S.P.A. DI RICERCHE BIOCHIMICHE (IT) 2023-10-26 US disclosed
US-20170202980-A1 METHOD FOR PRODUCING OPTICAL IMAGING CONTRAST AGENT AND OPTICAL IMAGING CONTRAST AGENT CANON KABUSHIKI KAISHA (JP) 2017-07-20 US disclosed
US-8153440-B2 Methods for altering surface characteristics of microspheres LUMINEX CORPORATION (US) 2012-04-10 US disclosed
US-20110086431-A1 Methods for Altering Surface Characteristics of Microspheres LUMINEX CORPORATION (US) 2011-04-14 US disclosed
US-7867774-B2 Methods for altering surface characteristics of microspheres LUMINEX CORPORATION (US) 2011-01-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170202980-A1 METHOD FOR PRODUCING OPTICAL IMAGING CONTRAST AGENT AND OPTICAL IMAGING CONTRAST AGENT ALB, FABP7, TTR NPSR1 4282/4885MAPT 166/4885HTT 2911/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.