SCHEMBL11090136

SCHEMBL11090136

CCCCCCCC(=O)Oc1cccc2oc3ccccc3c12

nearest known ligand 0.51

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
POLM Q9NP87 2/20 0.51
POLK Q9UBT6 2/20 0.51
POLL Q9UGP5 2/20 0.51
POLH Q9Y253 2/20 0.51
KDM4E B2RXH2 1/20 0.49
MEN1 O00255 1/20 0.49
RECQL P46063 1/20 0.49
KMT2A Q03164 1/20 0.49
FPR1 P21462 1/20 0.46
HTR2A P28223 1/20 0.43
PPARG P37231 1/20 0.43
ADRB2 P07550 1/20 0.43
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
ALOX15 P16050 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6601225 0.91 ADRB2 (0.47) KDM4EMEN1RECQLKMT2AADRB2
SCHEMBL19642798 0.81 POLM (0.55) POLMPOLKPOLLPOLHKDM4E
SCHEMBL21043909 0.81 ALDH1A1 (0.52) POLMPOLKPOLLPOLHKDM4E
SCHEMBL15548029 0.80 KDM4E (0.62) POLMPOLKPOLLPOLHKDM4E
SCHEMBL15547538 0.80 KDM4E (0.62) POLMPOLKPOLLPOLHKDM4E
SCHEMBL15548717 0.80 KDM4E (0.62) POLMPOLKPOLLPOLHKDM4E
SCHEMBL15547336 0.80 KDM4E (0.62) POLMPOLKPOLLPOLHKDM4E
SCHEMBL15550069 0.80 KDM4E (0.62) POLMPOLKPOLLPOLHKDM4E
SCHEMBL15548290 0.80 KMT2A (0.66) POLMPOLKPOLLPOLHKDM4E
SCHEMBL10571781 0.80 KMT2A (0.66) POLMPOLKPOLLPOLHKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4490550-A Preparation of dibenzofuran ASHLAND OIL, INC. (US) 1984-12-25 US disclosed