Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.48 |
| ▸ | POLM | Q9NP87 | 1/20 | 0.47 |
| ▸ | POLK | Q9UBT6 | 1/20 | 0.47 |
| ▸ | POLL | Q9UGP5 | 1/20 | 0.47 |
| ▸ | POLH | Q9Y253 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21194996 | 0.85 | ALDH1A1 (0.54) | ALDH1A1KMT2AMEN1TP53TSHR | |
| SCHEMBL24523066 | 0.84 | ALDH1A1 (0.59) | ALDH1A1KMT2AMEN1TP53TSHR | |
| SCHEMBL11090136 | 0.81 | POLM (0.51) | KMT2AMEN1POLMPOLKPOLL | |
| SCHEMBL24237029 | 0.80 | KCNA3 (0.72) | CYP1A2CYP3A4CYP2C9CYP2C19KCNA3 | |
| SCHEMBL24523105 | 0.80 | KCNA3 (0.72) | CYP1A2CYP3A4CYP2C9CYP2C19KCNA3 | |
| SCHEMBL14802497 | 0.80 | KCNA3 (0.72) | CYP1A2CYP3A4CYP2C9CYP2C19KCNA3 | |
| SCHEMBL29054840 | 0.80 | KCNA3 (0.64) | KMT2AMEN1PTGS2KCNA3CA12 | |
| SCHEMBL29054926 | 0.80 | KCNA3 (0.64) | KMT2AMEN1PTGS2KCNA3CA12 | |
| SCHEMBL20428408 | 0.80 | FPR1 (0.43) | TP53PTGS2CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL20420765 | 0.80 | FPR1 (0.43) | TP53PTGS2CYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11519014-B2 | Specific substrate of an ALDH isoenzyme | ADVANCED BIODESIGN (FR) | 2022-12-06 | — | — | US | disclosed |
| US-20190233871-A1 | SPECIFIC SUBSTRATE OF AN ALDH ISOENZYME | ADVANCED BIODESIGN (FR) | 2019-08-01 | — | — | US | disclosed |
| EP-3491143-A1 | SPECIFIC SUBSTRATE OF AN ALDH ISOENZYME | Advanced Biodesign (FR) | 2019-06-05 | — | — | EP | disclosed |