Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 3/20 | 0.35 |
| ▸ | CNR2 | P34972 | 10/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 6/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8378260 | 0.85 | HTR7 (0.47) | HTR7ALOX15MEN1KMT2AALDH1A1 | |
| SCHEMBL11078392 | 0.82 | HTR7 (0.45) | HTR7ALOX15MEN1KMT2AALDH1A1 | |
| SCHEMBL11041935 | 0.81 | HTR7 (0.44) | HTR7ALOX15MEN1KMT2AALDH1A1 | |
| SCHEMBL11016899 | 0.80 | ALOX15 (0.46) | HTR7ALOX15MEN1KMT2AALDH1A1 | |
| SCHEMBL17736981 | 0.78 | HTR7 (0.42) | HTR7ALOX15MEN1KMT2AALDH1A1 | |
| SCHEMBL11296309 | 0.78 | ALOX15 (0.42) | HTR7ALOX15MEN1KMT2AALDH1A1 | |
| SCHEMBL22572570 | 0.78 | HTR7 (0.46) | HTR7ALOX15MEN1KMT2AALDH1A1 | |
| SCHEMBL22572627 | 0.77 | HTR7 (0.45) | HTR7ALOX15MEN1KMT2AALDH1A1 | |
| SCHEMBL17736995 | 0.76 | HTR7 (0.39) | HTR7ALOX15MEN1KMT2AALDH1A1 | |
| SCHEMBL17736739 | 0.76 | HTR7 (0.41) | HTR7ALOX15MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0124342-A2 | Process for preparing isoxazolyl imidazolidinones | ELI LILLY AND COMPANY (US) | 1984-11-07 | — | — | EP | claimed |
| EP-0124342-A2 | Process for preparing isoxazolyl imidazolidinones | ELI LILLY AND COMPANY (US) | 1984-11-07 | — | — | EP | disclosed |