Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.44 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.44 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.44 |
| ▸ | FEN1 | P39748 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11092121 | 0.85 | CES2 (0.52) | L3MBTL1CYP1A2PKMMAPTKMT2A | |
| SCHEMBL993113 | 0.79 | TSHR (0.59) | TSHRALOX12L3MBTL1JAK2TAS1R3 | |
| SCHEMBL5955449 | 0.79 | TSHR (0.63) | TSHRALOX12L3MBTL1JAK2TAS1R3 | |
| SCHEMBL36590 | 0.79 | TSHR (0.63) | TSHRALOX12L3MBTL1JAK2TAS1R3 | |
| SCHEMBL29566931 | 0.79 | TSHR (0.63) | TSHRALOX12L3MBTL1JAK2TAS1R3 | |
| SCHEMBL16004864 | 0.78 | TSHR (0.50) | TSHRL3MBTL1ATMTP53LMNA | |
| Hydrochloric Acid SCHEMBL980715 | 0.78 | TSHR (0.57) | TSHRALOX12L3MBTL1JAK2TAS1R3 | |
| SCHEMBL3829070 | 0.77 | TSHR (0.61) | TSHRALOX12L3MBTL1JAK2TAS1R3 | |
| SCHEMBL29757660 | 0.77 | TSHR (0.61) | TSHRALOX12L3MBTL1JAK2TAS1R3 | |
| Potassium SCHEMBL30901224 | 0.77 | TSHR (0.48) | TSHRL3MBTL1ATMTP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4470932-A | TRIMETHYL SILYL CARBOXYLATE AND CARBOXYLIC ACID CHLORIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1984-09-11 | — | — | US | disclosed |