SCHEMBL36590

SCHEMBL36590

O=C(OOC(=O)c1cccc(Cl)c1Cl)c1cccc(Cl)c1Cl

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.63
L3MBTL1 Q9Y468 2/20 0.50
ERCC5 P28715 1/20 0.50
FEN1 P39748 1/20 0.50
ALOX12 P18054 1/20 0.50
P2RX7 Q99572 1/20 0.49
ATM Q13315 1/20 0.48
CES2 O00748 1/20 0.46
CES1 P23141 1/20 0.46
JAK2 O60674 1/20 0.46
TAS1R3 Q7RTX0 1/20 0.46
TAS1R1 Q7RTX1 1/20 0.46
TAS1R2 Q8TE23 1/20 0.46
ALDH1A1 P00352 4/20 0.45
PKM P14618 2/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2C19 P33261 1/20 0.44
POLB P06746 1/20 0.42
KMT2A Q03164 2/20 0.41
MEN1 O00255 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29566931 1.00 TSHR (0.63) TSHRL3MBTL1ERCC5FEN1ALOX12
SCHEMBL4477586 0.89 F2 (0.59) TSHRL3MBTL1ERCC5FEN1ALOX12
SCHEMBL5955449 0.87 TSHR (0.63) TSHRL3MBTL1ERCC5FEN1ALOX12
SCHEMBL1396707 0.86 MAPT (0.49) TSHRL3MBTL1ALDH1A1PKMCYP1A2
SCHEMBL3829070 0.85 TSHR (0.61) TSHRL3MBTL1ERCC5FEN1ALOX12
SCHEMBL29757660 0.85 TSHR (0.61) TSHRL3MBTL1ERCC5FEN1ALOX12
SCHEMBL1311788 0.85 TSHR (0.47) TSHRL3MBTL1ERCC5FEN1ALOX12
Isopropylbenzene SCHEMBL6796969 0.85 TSHR (0.51) TSHRL3MBTL1ERCC5FEN1ALOX12
SCHEMBL993113 0.83 TSHR (0.59) TSHRL3MBTL1ERCC5FEN1ALOX12
SCHEMBL36252 0.82 CES2 (0.62) L3MBTL1ERCC5FEN1CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3397 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119931249-A Thermoplastic modified insulating material and preparation method and application thereof 中国石油化工股份有限公司 2025-05-06 CN claimed
CN-119912641-A Modified polypropylene dielectric energy storage material and preparation method and application thereof 中国石油化工股份有限公司 2025-05-02 CN claimed
CN-110627630-B Treatment method of diacyl peroxide waste 江苏强盛功能化学股份有限公司 2024-08-27 CN claimed
CN-118546340-A Polyester, and preparation and purification methods and application thereof 上海化工研究院有限公司 2024-08-27 CN claimed
CN-117106403-B Flexible solvent-free double-component PU (polyurethane) structural adhesive and preparation method thereof 韦尔通科技股份有限公司 2024-06-04 CN claimed
CN-117903724-A Photo-curing acrylic resin pressure-sensitive adhesive and preparation method thereof 福州恒美光电材料有限公司 2024-04-19 CN claimed
CN-117106403-A Flexible solvent-free double-component PU (polyurethane) structural adhesive and preparation method thereof 韦尔通科技股份有限公司 2023-11-24 CN claimed
CN-115746699-B Transparent organic silicon coating adhesive composition and preparation method and application thereof 杭州之江有机硅化工有限公司 2023-10-31 CN claimed
CN-113801492-B Wave-absorbing composite foam material and preparation method thereof 湖南兆恒材料科技有限公司 2023-08-25 CN claimed
CN-113107526-B Anti-impact ground pressure supporting method suitable for forming roadway 淮北市平远软岩支护工程技术有限公司 2023-05-16 CN claimed
EP-0100873-A1 Heat-curing polysiloxane compositions BAYER AG (DE) 1984-02-22 EP claimed
US-4415603-A HIGH-SPEED ULTRAVIOLET RADIATION POLYMERIZATION OF AN ACRYLATE, UNSATURATED MONOMERS, PHOTOINITIATOR, PEROXIDE AND REDUCING SALT COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 1983-11-15 US claimed
US-4412042-A SOLVENT-FREE, VAPOR PHASE POLYMERIZATION OF ETHYLENE AND A-OLEFIN IN PRESENCE OF CATALYSTS, THEN REACTION WITH SILANE COMPOUND NIPPON OIL COMPANY, LIMITED (JP) 1983-10-25 US claimed
US-4164491-A DIORGANOPOLYSILOXANE GUM, POLYURETHANE ELASTOMER, REINFORCING FILLER, ORGANIC PEROXIDE SHIN-ETSU CHEMICAL CO., LTD. (JP) 1979-08-14 US claimed
US-4113690-A Silicone elastomers containing alkoxysiloxanols SWS SILICONES CORPORATION (US) 1978-09-12 US claimed
US-4064312-A Nonimaged waterless lithographic master with a curable silicone elastomer and a cured ink releasable silicone layer XEROX CORPORATION (US) 1977-12-20 US claimed
US-4033983-A TERTELOMERS OF VINYL CHLORIDE, DIALKYL MALEATE, BIS(2-CHLOROETHYL)VINYL PHOSPHONATE CONTINENTAL OIL COMPANY (US) 1977-07-05 US claimed
US-4016328-A SILICONE RESIN, SILICONE GUM, 2,4-DICHLOROBENZOYL PEROXIDE AS CURING AGENT GENERAL ELECTRIC COMPANY (US) 1977-04-05 US claimed
US-4006202-A Polymer composition COSDEN OIL & CHEMICAL COMPANY (US) 1977-02-01 US claimed
US-3956244-A COPOLYMERIZATION N L INDUSTRIES, INC. (US) 1976-05-11 US claimed