Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | PKM | P14618 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16004864 | 0.86 | TSHR (0.50) | ALDH1A1POLBNPC1L3MBTL1LMNA | |
| SCHEMBL11090263 | 0.85 | TSHR (0.53) | CES2CES1RAB9APKMNPC1 | |
| Potassium SCHEMBL30901224 | 0.84 | TSHR (0.48) | ALDH1A1POLBNPC1L3MBTL1LMNA | |
| SCHEMBL30778085 | 0.78 | LMNA (0.62) | ALDH1A1RAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL28213276 | 0.78 | L3MBTL1 (0.48) | ALDH1A1RAB9APKMNPC1HPGD | |
| SCHEMBL28064610 | 0.78 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2HPGDMAPTLMNA | |
| SCHEMBL30488606 | 0.78 | LMNA (0.61) | CES2CES1ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL27861348 | 0.78 | CES2 (0.58) | CES2CES1ALDH1A1POLBRAB9A | |
| SCHEMBL196555 | 0.78 | LMNA (0.61) | CES2CES1ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL2153551 | 0.77 | CES2 (0.62) | CES2CES1ALDH1A1POLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4470932-A | TRIMETHYL SILYL CARBOXYLATE AND CARBOXYLIC ACID CHLORIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1984-09-11 | — | — | US | disclosed |