Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 17/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1104986 | 0.92 | SLC22A12 (0.47) | SCN9ASLC22A12CYP2C9 | |
| SCHEMBL1094339 | 0.82 | SCN8A (0.43) | SCN9ASLC22A12 | |
| SCHEMBL1109046 | 0.82 | SCN9A (0.56) | SCN9ACYP2C9 | |
| SCHEMBL1094795 | 0.80 | SLC22A12 (0.51) | SCN9ASLC22A12CYP2C9 | |
| SCHEMBL17270526 | 0.80 | SCN9A (0.43) | SCN9ASLC22A12 | |
| SCHEMBL17270560 | 0.79 | SCN9A (0.46) | SCN9ASLC22A12CYP2C9 | |
| SCHEMBL1095192 | 0.75 | SCN9A (0.66) | SCN9ACYP2C9 | |
| SCHEMBL20252600 | 0.74 | SCN8A (0.61) | SCN9ACYP2C9 | |
| SCHEMBL20259304 | 0.72 | SCN8A (0.51) | SCN9ACYP2C9 | |
| SCHEMBL19627632 | 0.71 | SCN8A (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120149679-A1 | Sulfonamide Derivatives | ICAGEN, INC. | 2012-06-14 | — | — | US | disclosed |
| US-8153814-B2 | Sulfonamide derivatives | PFIZER LIMITED (GB) | 2012-04-10 | — | — | US | disclosed |
| US-20100197655-A1 | SULFONAMIDE DERIVATIVES | Pfizer Limited Icagen, Inc. | 2010-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100197655-A1 | SULFONAMIDE DERIVATIVES | SULT2A1, SULT1A1, TPST2 | SCN9A 73/4885SLC22A12 999/4885CYP2C9 75/4885 |
| US-20120149679-A1 | Sulfonamide Derivatives | SULT2A1, SULT1A1, TPST2 | SCN9A 73/4885SLC22A12 999/4885CYP2C9 75/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.