⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18983058 | 0.83 | ALOX5 (0.31) | — | |
| SCHEMBL9946484 | 0.79 | — | — | |
| SCHEMBL9700115 | 0.78 | CYP3A4 (0.36) | — | |
| SCHEMBL3657249 | 0.77 | AKR1B1 (0.41) | — | |
| SCHEMBL4651248 | 0.74 | — | — | |
| SCHEMBL4582881 | 0.70 | MAOB (0.47) | — | |
| SCHEMBL588597 | 0.69 | — | — | |
| SCHEMBL6665441 | 0.67 | MMP2 (0.50) | — | |
| SCHEMBL6021918 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL22711054 | 0.67 | MMP2 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230293459-A1 | OLEYLCYSTEINEAMIDE OR DERIVATIVES THEREOF AND THEIR USE IN THERAPY | HADASIT MEDICAL RESEARCH SERVICES & DEVELOPMENT LIMITED (IL) | 2023-09-21 | — | — | US | disclosed |
| CN-116437907-A | Oleyl cystein amides or derivatives thereof and their use in therapy | 耶路撒冷希伯来大学伊森姆研究发展有限公司 | 2023-07-14 | — | — | CN | disclosed |
| EP-4192441-A1 | OLEYLCYSTEINEAMIDE OR DERIVATIVES THEREOF AND THEIR USE IN THERAPY | Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. (IL) | 2023-06-14 | — | — | EP | disclosed |
| WO-2022029785-A1 | OLEYLCYSTEINEAMIDE OR DERIVATIVES THEREOF AND THEIR USE IN THERAPY | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2022-02-10 | — | — | WO | disclosed |
| US-4471129-A | ANTIHISTAMINES | LILLY INDUSTRIES LIMITED (GB) | 1984-09-11 | — | — | US | disclosed |