Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | NAT1 | P18440 | 1/20 | 0.30 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11091048 | 0.78 | — | — | |
| SCHEMBL9946484 | 0.76 | — | — | |
| SCHEMBL18983058 | 0.75 | ALOX5 (0.31) | TRPA1ALOX5MMP2 | |
| SCHEMBL28898226 | 0.75 | — | — | |
| SCHEMBL3657249 | 0.73 | AKR1B1 (0.41) | — | |
| SCHEMBL29064117 | 0.69 | — | — | |
| SCHEMBL9625778 | 0.67 | BCL2 (0.33) | ALOX5 | |
| SCHEMBL588597 | 0.66 | — | — | |
| SCHEMBL6665441 | 0.64 | MMP2 (0.50) | MMP2 | |
| SCHEMBL7712387 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111620893-B | C-3 tetrahydrofuran substituted cephalosporin-siderophore coupling compound and preparation method and application thereof | 重庆医药高等专科学校 | 2021-12-14 | — | — | CN | disclosed |
| CN-111620893-A | C-3 tetrahydrofuran substituted cephalosporin-siderophore coupling compound and preparation method and application thereof | 重庆医药高等专科学校 | 2020-09-04 | — | — | CN | disclosed |
| WO-1992012131-A1 | 3-HYDROXYPYRIDIN-4-ONE DERIVATIVES AS PHARMACEUTICAL COMPOSITIONS | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1992-07-23 | — | — | WO | disclosed |
| EP-0494754-A1 | 3-hydroxypyridin-4-one derivatives as pharmaceutical compositions | BRITISH TECHNOLOGY GROUP LTD (GB) | 1992-07-15 | — | — | EP | disclosed |