Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 8/20 | 0.40 |
| ▸ | CTSS | P25774 | 8/20 | 0.40 |
| ▸ | SDCBP | O00560 | 1/20 | 0.39 |
| ▸ | SDC2 | P34741 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 2/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11091216 | 1.00 | NAMPT (0.41) | NAMPTHDAC1HDAC2CTSKCTSS | |
| SCHEMBL11088546 | 0.87 | CYP17A1 (0.41) | CTSKCTSSATMMAPT | |
| SCHEMBL11088554 | 0.87 | CYP17A1 (0.41) | CTSKCTSSATMMAPT | |
| SCHEMBL11088548 | 0.87 | CYP17A1 (0.41) | CTSKCTSSATMMAPT | |
| SCHEMBL23414380 | 0.84 | HDAC1 (0.38) | HDAC1HDAC2CTSKCTSSATM | |
| SCHEMBL11088568 | 0.80 | RORC (0.39) | HDAC1HDAC2CTSKCTSSATM | |
| SCHEMBL11088569 | 0.80 | RORC (0.39) | HDAC1HDAC2CTSKCTSSATM | |
| SCHEMBL11088574 | 0.80 | RORC (0.39) | HDAC1HDAC2CTSKCTSSATM | |
| SCHEMBL9327248 | 0.79 | MAPT (0.46) | HDAC1HDAC2ATML3MBTL1MAPT | |
| SCHEMBL9567734 | 0.79 | MAPT (0.46) | HDAC1HDAC2ATML3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4464366-A | Cephem compounds having a terminal aminocarboxylic acid grouping and containing an azacyclyl(thio)ureido group | CIBA GEIGY CORPORATION (US) | 1984-08-07 | — | — | US | disclosed |