Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.37 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 2/20 | 0.35 |
| ▸ | NPY1R | P25929 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11088574 | 1.00 | RORC (0.39) | RORCCTSSCTSKPOLBACSS2 | |
| SCHEMBL11088568 | 1.00 | RORC (0.39) | RORCCTSSCTSKPOLBACSS2 | |
| SCHEMBL11088554 | 0.89 | CYP17A1 (0.41) | CTSSCTSKPOLBACSS2ATM | |
| SCHEMBL11088548 | 0.89 | CYP17A1 (0.41) | CTSSCTSKPOLBACSS2ATM | |
| SCHEMBL11088546 | 0.89 | CYP17A1 (0.41) | CTSSCTSKPOLBACSS2ATM | |
| SCHEMBL11083541 | 0.88 | ATM (0.35) | CTSSCTSKPOLBATMHDAC1 | |
| SCHEMBL11083550 | 0.88 | ATM (0.35) | CTSSCTSKPOLBATMHDAC1 | |
| SCHEMBL11083551 | 0.82 | BRD4 (0.38) | CTSSCTSKPOLBATMHDAC1 | |
| SCHEMBL16019036 | 0.82 | KEAP1 (0.37) | POLBATMBACE1HDAC1HDAC2 | |
| SCHEMBL8597022 | 0.80 | ATM (0.42) | POLBATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4464366-A | Cephem compounds having a terminal aminocarboxylic acid grouping and containing an azacyclyl(thio)ureido group | CIBA GEIGY CORPORATION (US) | 1984-08-07 | — | — | US | disclosed |