Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 8/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.43 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11085127 | 0.88 | ADORA3 (0.60) | KDM4EADORA3ALDH1A1HPGDTSHR | |
| SCHEMBL11081690 | 0.86 | ADORA3 (0.60) | LMNAKDM4EADORA3ALDH1A1HPGD | |
| SCHEMBL11164594 | 0.84 | KDM4E (0.49) | LMNAKDM4EALDH1A1HPGDTSHR | |
| SCHEMBL11090098 | 0.84 | ADORA3 (0.55) | LMNAKDM4EADORA3ALDH1A1HPGD | |
| SCHEMBL11088361 | 0.82 | ADORA3 (0.56) | LMNAKDM4EADORA3ALDH1A1HTT | |
| SCHEMBL11087927 | 0.82 | ADORA3 (0.67) | KDM4EADORA3ALDH1A1TSHRHSD17B10 | |
| SCHEMBL10969977 | 0.76 | LMNA (0.56) | LMNAKDM4EALDH1A1HPGDTSHR | |
| Melquinast SCHEMBL2109337 | 0.75 | ADORA3 (0.56) | KDM4EADORA3ALDH1A1HPGDTSHR | |
| SCHEMBL11082599 | 0.73 | ADORA3 (0.48) | ADORA3 | |
| SCHEMBL11089751 | 0.72 | PGR (0.48) | LMNAKDM4EADORA3ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4463007-A | ANTIALLERGENS | BASF AKTIENGESELLSCHAFT (DE) | 1984-07-31 | — | — | US | disclosed |