Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | EGFR | P00533 | 3/20 | 0.39 |
| ▸ | SRC | P12931 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | GLA | P06280 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | RGS12 | O14924 | 1/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.39 |
| ▸ | PRKCG | P05129 | 1/20 | 0.39 |
| ▸ | PRKCB | P05771 | 1/20 | 0.39 |
| ▸ | PRKCA | P17252 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10711888 | 0.75 | BRD4 (0.40) | MAPTALDH1A1KDM4EHPGDNPSR1 | |
| SCHEMBL117727 | 0.73 | CACNB4 (0.40) | MAPTALDH1A1TDP1HPGDSMN1; SMN2 | |
| SCHEMBL11085902 | 0.72 | HTR1A (0.38) | KMT2ALMNAGAA | |
| SCHEMBL11478104 | 0.71 | AKR1C3 (0.39) | MAPTALDH1A1KMT2ATDP1SMN1; SMN2 | |
| SCHEMBL1321330 | 0.71 | HTR2C (0.46) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL10712953 | 0.70 | IDO1 (0.35) | MAPTALDH1A1MEN1KMT2AEGFR | |
| SCHEMBL11091290 | 0.69 | MEN1 (0.38) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL11093677 | 0.68 | CACNB4 (0.36) | MAPTALDH1A1HPGDSMN1; SMN2NPSR1 | |
| SCHEMBL11093153 | 0.67 | IDO1 (0.38) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL10712554 | 0.67 | KMT2A (0.45) | MAPTALDH1A1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4472433-A | Phenoxyphenyl acetic acids and their medicinal use | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-09-18 | — | — | US | disclosed |
| EP-0008226-A2 | Phenyl-alkanoic acid derivatives, the preparation thereof and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-02-20 | — | — | EP | disclosed |