Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KDM4A | O75164 | 1/20 | 0.45 |
| ▸ | TDP2 | O95551 | 1/20 | 0.45 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.45 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | S100A4 | P26447 | 2/20 | 0.38 |
| ▸ | PTPRC | P08575 | 1/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | DNMT3B | Q9UBC3 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10714343 | 0.85 | LMNA (0.41) | KMT2AMEN1KDM4ATDP2KDM4C | |
| SCHEMBL10712632 | 0.81 | PGR (0.39) | KMT2AMEN1TDP1SMN1; SMN2MAPT | |
| SCHEMBL10712211 | 0.80 | KMT2A (0.45) | KMT2AMEN1KDM4ATDP2KDM4C | |
| SCHEMBL10711063 | 0.79 | MEN1 (0.42) | KMT2AMEN1KDM4ATDP2KDM4C | |
| SCHEMBL10712953 | 0.79 | IDO1 (0.35) | KMT2AMEN1ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL10712822 | 0.79 | ALDH1A1 (0.40) | KMT2AALDH1A1PTPRCPOLBSMN1; SMN2 | |
| SCHEMBL10711888 | 0.78 | BRD4 (0.40) | ALDH1A1KDM4EMAPTCYP1A2CYP2C9 | |
| SCHEMBL10711782 | 0.77 | PGR (0.46) | KMT2AMEN1KDM4ATDP2KDM4C | |
| SCHEMBL10711944 | 0.76 | CREBBP (0.46) | KMT2AMEN1PTPRCPTPN1KDM4E | |
| SCHEMBL10711674 | 0.74 | MEN1 (0.42) | KMT2AMEN1KDM4ATDP2KDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670566-A | ANTIIFLAMMATORY AGENTS, ANTICOAGULANTS | A. H. ROBINS COMPANY, INCORPORATED (US) | 1987-06-02 | — | — | US | disclosed |
| US-4440785-A | Methods of using 2-aminobiphenylacetic acids, esters, and metal salts thereof to treat inflammation | A. H. ROBINS COMPANY, INC. (US) | 1984-04-03 | — | — | US | disclosed |