Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNB4 | O00305 | 2/20 | 0.40 |
| ▸ | CACNA1A | O00555 | 2/20 | 0.40 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.40 |
| ▸ | CACNG3 | O60359 | 2/20 | 0.40 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.40 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.40 |
| ▸ | CACNB3 | P54284 | 2/20 | 0.40 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.40 |
| ▸ | CACNG7 | P62955 | 2/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.40 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.40 |
| ▸ | CACNB1 | Q02641 | 2/20 | 0.40 |
| ▸ | CACNG1 | Q06432 | 2/20 | 0.40 |
| ▸ | CACNB2 | Q08289 | 2/20 | 0.40 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.40 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.40 |
| ▸ | CACNA1E | Q15878 | 2/20 | 0.40 |
| ▸ | CACNA2D4 | Q7Z3S7 | 2/20 | 0.40 |
| ▸ | CACNA2D3 | Q8IZS8 | 2/20 | 0.40 |
| ▸ | CACNG8 | Q8WXS5 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15966870 | 0.87 | AHR (0.62) | CACNB4CACNA1ACACNA1GCACNG3CACNA1F | |
| SCHEMBL10712822 | 0.86 | ALDH1A1 (0.40) | CACNB4CACNA1ACACNA1GCACNG3CACNA1F | |
| SCHEMBL11093677 | 0.86 | CACNB4 (0.36) | CACNB4CACNA1ACACNA1GCACNG3CACNA1F | |
| SCHEMBL11097244 | 0.84 | CACNA1B (0.37) | CACNB4CACNA1ACACNA1GCACNG3CACNA1F | |
| SCHEMBL11368672 | 0.81 | DAO (0.40) | DAOALDH1A1MAPTCA12CA1 | |
| SCHEMBL11094086 | 0.79 | HTR1A (0.34) | ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL10713399 | 0.78 | PGR (0.36) | CACNB4CACNA1ACACNA1GCACNG3CACNA1F | |
| SCHEMBL1321330 | 0.78 | HTR2C (0.46) | CACNA1BALDH1A1MAPTCYP2C9HPGD | |
| SCHEMBL24112933 | 0.77 | PGR (0.49) | CACNB4CACNA1ACACNA1GCACNG3CACNA1F | |
| SCHEMBL24112226 | 0.77 | PGR (0.49) | CACNB4CACNA1ACACNA1GCACNG3CACNA1F |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9242934-B2 | Process for the preparation of oxindoles and ortho-substituted anilines and their use as intermediates for syntheses | BAYER CROPSCIENCE AG (DE) | 2016-01-26 | — | — | US | disclosed |
| EP-2424835-B1 | METHOD FOR PRODUCING OXINDOLES AND ORTHO-SUBSTITUTED ANILINES | BAYER IP GMBH (DE) | 2015-07-01 | — | — | EP | disclosed |
| US-20130281711-A1 | PROCESS FOR THE PREPARATION OF OXINDOLES AND ORTHO-SUBSTITUTED ANILINES AND THEIR USE AS INTERMEDIATES FOR SYNTHESES | BAYER CROPSCIENCE AG (DE) | 2013-10-24 | — | — | US | disclosed |
| US-8563749-B2 | Process for preparing substituted 1,3-dihydro-2H-indol-2-ones | BAYER CROPSCIENCE AG (DE) | 2013-10-22 | — | — | US | disclosed |
| US-8492590-B2 | Process for the preparation of oxindoles and ortho-substituted anilines and their use as intermediates for syntheses | BAYER CROPSCIENCE AG (DE) | 2013-07-23 | — | — | US | disclosed |
| CN-102985406-A | Process for preparing substituted 1,3-dihydro-2h-indol-2-ones | BAYER CROPSCIENCE AG | 2013-03-20 | — | — | CN | disclosed |
| WO-2012028162-A1 | PROCESS FOR PREPARING OXINDOLES AND ORTHO-SUBSTITUTED ANILINES AND THE USE THEREOF AS INTERMEDIATES FOR SYNTHESES | BAYER CROPSCIENCE AG (DE) | 2012-03-08 | — | — | WO | disclosed |
| EP-2424835-A1 | METHOD FOR PRODUCING OXINDOLES AND ORTHO-SUBSTITUTED ANILINES AND THE USE THEREOF AS INTERMEDIATE PRODUCTS FOR SYNTHESES | Bayer CropScience AG (DE) | 2012-03-07 | — | — | EP | disclosed |
| US-20110275832-A1 | Process for Preparing Substituted 1,3-dihydro-2H-indol-2-ones | BAYER CROPSCIENCE AG (DE) | 2011-11-10 | — | — | US | disclosed |
| US-20110118478-A1 | PROCESS FOR THE PREPARATION OF OXINDOLES AND ORTHO-SUBSTITUTED ANILINES AND THEIR USE AS INTERMEDIATES FOR SYNTHESES | BAYER CROPSCIENCE AG (DE) | 2011-05-19 | — | — | US | disclosed |
| WO-2010127786-A1 | METHOD FOR PRODUCING OXINDOLES AND ORTHO-SUBSTITUTED ANILINES AND THE USE THEREOF AS INTERMEDIATE PRODUCTS FOR SYNTHESES | BAYER CROPSCIENCE AG (DE) | 2010-11-11 | — | — | WO | disclosed |
| EP-2246326-A1 | Method for producing oxindoles and ortho-substituted anilines and their use as intermediate products for syntheses | Bayer CropScience AG (DE) | 2010-11-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110118478-A1 | PROCESS FOR THE PREPARATION OF OXINDOLES AND ORTHO-SUBSTITUTED ANILINES AND THEIR USE AS INTERMEDIATES FOR SYNTHESES | TH, OXSR1, AOX1 | CACNB4 3953/4885CACNA1A 2765/4885CACNA1G 3890/4885 |
| US-20130281711-A1 | PROCESS FOR THE PREPARATION OF OXINDOLES AND ORTHO-SUBSTITUTED ANILINES AND THEIR USE AS INTERMEDIATES FOR SYNTHESES | TH, OXSR1, AOX1 | CACNB4 3953/4885CACNA1A 2765/4885CACNA1G 3890/4885 |
| US-20110275832-A1 | Process for Preparing Substituted 1,3-dihydro-2H-indol-2-ones | IDO1, IDO2, TDO2 | CACNB4 4582/4885CACNA1A 2930/4885CACNA1G 2412/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.