Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | GALR1 | P47211 | 1/20 | 0.35 |
| ▸ | PLA2G7 | Q13093 | 2/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | GSK3A | P49840 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11126029 | 0.75 | MEN1 (0.33) | SMN1; SMN2TSHRHSD11B1 | |
| SCHEMBL11094467 | 0.72 | ALDH1A1 (0.38) | SMN1; SMN2 | |
| SCHEMBL11125226 | 0.71 | SMN1; SMN2 (0.34) | SMN1; SMN2HTR1AADRA1B | |
| SCHEMBL11096938 | 0.69 | HTR1A (0.32) | SMN1; SMN2HTR1AADRA1B | |
| SCHEMBL10079774 | 0.69 | ALDH1A1 (0.37) | SMN1; SMN2HDAC4TSHR | |
| SCHEMBL10079502 | 0.68 | LMNA (0.36) | SMN1; SMN2GALR1P2RX7 | |
| SCHEMBL11331757 | 0.68 | LMNA (0.35) | SMN1; SMN2GSK3B | |
| SCHEMBL13263919 | 0.68 | SMN1; SMN2 (0.35) | SMN1; SMN2TSHR | |
| SCHEMBL11093637 | 0.68 | BRD4 (0.38) | SMN1; SMN2 | |
| SCHEMBL10898897 | 0.67 | NOTUM (0.41) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4436666-A | HERBICIDES, MITICIDWS | UNION CARBIDE CORPORATION (US) | 1984-03-13 | — | — | US | disclosed |