Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.33 |
| ▸ | IGF1R | P08069 | 2/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.33 |
| ▸ | NTRK2 | Q16620 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MMP14 | P50281 | 2/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | PNLIP | P16233 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.32 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.32 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11093677 | 0.70 | CACNB4 (0.36) | CYP1A2CYP2C9CYP2C19MMP14MMP13 | |
| SCHEMBL11092601 | 0.68 | MMP14 (0.37) | CYP1A2CYP2C9CYP2C19MMP14MMP13 | |
| SCHEMBL117727 | 0.67 | CACNB4 (0.40) | CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11088266 | 0.67 | AHR (0.49) | FFAR1 | |
| SCHEMBL11091196 | 0.64 | MAOA (0.47) | NTRK1IGF1RFGFR1NTRK2MMP13 | |
| Ethane SCHEMBL27569819 | 0.61 | DPP4 (0.58) | CYP1A2CYP3A4CYP2C9CYP2C19DPP4 | |
| SCHEMBL3790160 | 0.61 | DPP4 (0.62) | CYP1A2CYP3A4CYP2C9CYP2C19DPP4 | |
| SCHEMBL11091290 | 0.60 | MEN1 (0.38) | CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL304918 | 0.60 | CYP1A2 (0.48) | CYP1A2CYP3A4CYP2C9CYP2C19DPP4 | |
| SCHEMBL21295423 | 0.60 | NTRK1 (0.61) | NTRK1IGF1RFGFR1NTRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4472433-A | Phenoxyphenyl acetic acids and their medicinal use | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-09-18 | — | — | US | disclosed |
| EP-0008226-B1 | PHENYL-ALKANOIC ACID DERIVATIVES, THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-11-02 | — | — | EP | disclosed |
| EP-0008226-A2 | Phenyl-alkanoic acid derivatives, the preparation thereof and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-02-20 | — | — | EP | disclosed |